152656-88-7

Basic information

• Product Name: 3-Methyl-5-(toluene-4-sulfonyl)-4-p-tolyl-1,5-dihydro-pyrrol-2-one
• Synonyms: 3-Methyl-5-(toluene-4-sulfonyl)-4-p-tolyl-1,5-dihydro-pyrrol-2-one
• CAS NO: 152656-88-7
• Molecular Weight: 341.431
• Mol File: 152656-88-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 3-Methyl-5-(toluene-4-sulfonyl)-4-p-tolyl-1,5-dihydro-pyrrol-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Methyl-5-(toluene-4-sulfonyl)-4-p-tolyl-1,5-dihydro-pyrrol-2-one(152656-88-7)
• EPA Substance Registry System: 3-Methyl-5-(toluene-4-sulfonyl)-4-p-tolyl-1,5-dihydro-pyrrol-2-one(152656-88-7)

Safety Data

• Hazardous Substances Data: 152656-88-7(Hazardous Substances Data)

Upstream product

• 152797-10-9 2-Bromo-3-methyl-5-(toluene-4-sulfonyl)-4-p-tolyl-1H-pyrrole 
• 536-57-2 p-toluene sulfinic acid 
• 263898-73-3 5-acetoxy-5-(t-butoxycarbonyl)-1,5-dihydro-3-methyl-4-(p-tolyl)-2H-pyrrol-2-one 
• 263898-69-7 t-butyl 5-iodo-4-methyl-3-(p-tolyl)-2-pyrrolecarboxylate 

Downstream Products

• 2850-19-3 (toluene-4-sulfonyl)-acetic acid ethyl ester 
• 924-44-7 glyoxylic acid ethyl ester 
• 152656-73-0 (E)-1,5-dihydro-3-methyl-4-(p-tolyl)-5-(p-tolylmethylene)-2H-pyrrol-2-one 

Relevant articles and documents

An efficient method to construct the A,B-rings component toward total syntheses of phycocyanobilin and its derivative as a photoprobe

Total syntheses of physocyanobilin and its derivative bearing a photoreactive group at the D-ring accomplished by developing a new and efficient method for the construction of A,B-rings component, which consists of the Wittig-type new coupling reaction of 4-(1-methoxyethyl or 1- tosylethyl)-3-methyl-5-tosyl-1,5-dihydro-2H-pyrrol-2-one and a 2-formyl pyrrole derivative in the presence of (n)Bu3P and a base, followed by reduction with aluminum amalgam and a subsequent acid or base treatment.

Convenient and Regioselective Syntheses of 3,4-Disubstituted Δ3-Pyrrolin-2-ones Derivatives Starting from 2-Tosyl-3,4-Disubstituted Pyrroles

3,4-Disubstituted Δ3-pyrrolin-2-ones were prepared in high yields via 5-tosyl-Δ3-pyrrolin-2-ones (4) starting from 2-tosylpyrroles regioselectively.The compounds 4 were found to be useful intermediates for the preparation of variety of Δ3-pyrrolin-2-one derivatives.The reactions of 4 with various nucleophiles and active methylene compounds bearing an appropriate leaving group are described.