1527-84-0

Basic information

• Product Name: Benzaldehyde, 4-hydroxy-3-methoxy-, hydrazone
• CAS NO: 1527-84-0
• Molecular Formula: C8H10N2O2
• Molecular Weight: 166.18
• Mol File: 1527-84-0.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: Benzaldehyde, 4-hydroxy-3-methoxy-, hydrazone(CAS DataBase Reference)
• NIST Chemistry Reference: Benzaldehyde, 4-hydroxy-3-methoxy-, hydrazone(1527-84-0)
• EPA Substance Registry System: Benzaldehyde, 4-hydroxy-3-methoxy-, hydrazone(1527-84-0)

Safety Data

• Hazardous Substances Data: 1527-84-0(Hazardous Substances Data)

Upstream product

• 387363-94-2 2-((4-hydroxy-3-methoxybenzylidene)amino)-1H-benzo[de]isoquinoline-1,3(2H)-dione 
• 134283-49-1 (E)-4-hydroxy-3-methoxybenzaldehyde oxime 
• 121-33-5 vanillin 

Downstream Products

• 2874-33-1 vanillin oxime 
• 2092-49-1 6,6'-dihydroxy-5,5'-dimethoxy-biphenyl-3,3'-dicarbaldehyde 
• 214854-34-9 4-(((4H-1,2,4-triazol-4-yl)imino)methyl)-2-methoxyphenol 
• 121-33-5 vanillin 
• 16742-60-2 vanillin semicarbazone 
• 4421-08-3 3-methoxy-4-hydroxybenzonitrile 
• 93-51-6 2-Methoxy-4-methylphenol 

Relevant articles and documents

A novel one pot multi-component strategy for facile synthesis of 5-aryl-[1,2,4]triazolidine-3-thiones

We have disclosed an efficient, one pot, novel multi-component approach for the synthesis of 5-aryl-[1,2,4]triazolidine-3-thiones from aldehyde, hydrazine hydrate, and trimethylsilyl isothiocyanate (TMSNCS) in the presence of catalytic amount of sulfamic acid. High yields, easy work-up procedure, no chromatographic separation, and novelty in multi-component strategy are the main merits of the present strategy.

N-Amino-1,8-Naphthalimide is a Regenerated Protecting Group for Selective Synthesis of Mono-N-Substituted Hydrazines and Hydrazides

A new route to synthesis of various mono-N-substituted hydrazines and hydrazides by involving in a new C?N bond formation by using N-amino-1,8-naphthalimide as a regenerated precursor was invented. Aniline and phenylhydrazines are reproduced upon reacting these individually with 1,8-naphthalic anhydride followed by hydrazinolysis. The practicality and simplicity of this C?N dihalo alkanes; developed a synthon for bond formation protocol was exemplified to various hydrazines and hydrazides. N-amino-1,8-naphthalimide is suitable synthon for transformation for selective formation of mono-substituted hydrazine and hydrazide derivatives. Those are selective mono-amidation of hydrazine with acid halides; mono-N-substituted hydrazones from aldehydes; synthesis of N-aminoazacycloalkanes from acetohydrazide scaffold and inserted to hydroxy derivatives; distinct synthesis of N,N-dibenzylhydrazines and N-benzylhydrazines from benzyl halides; synthesis of N-amino-amino acids from α-halo esters. Ecofriendly reagent N-amino-1,8-naphthalimide was regenerated with good yields by the hydrazinolysis in all procedures.

Structure-based design, synthesis, and biological evaluation of novel piperine-resveratrol hybrids as antiproliferative agents targeting SIRT-2

A series of novel piperine-resveratrol hybrids5a-hwas designed, synthesized, and structurally elucidated by IR, and1H,13C, and19F NMR. Antiproliferative activities of5a-hwere evaluated by NCI against sixty cancer cell line