152846-62-3

Basic information

• Product Name: Benzonitrile, 4-(1,3,2-dioxaborinan-2-yl)-
• CAS NO: 152846-62-3
• Molecular Formula: C10H10BNO2
• Molecular Weight: 187.006
• Mol File: 152846-62-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Benzonitrile, 4-(1,3,2-dioxaborinan-2-yl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzonitrile, 4-(1,3,2-dioxaborinan-2-yl)-(152846-62-3)
• EPA Substance Registry System: Benzonitrile, 4-(1,3,2-dioxaborinan-2-yl)-(152846-62-3)

Safety Data

• Hazardous Substances Data: 152846-62-3(Hazardous Substances Data)

Upstream product

• 126747-14-6 4-cyanophenylboronic acid 
• 504-63-2 trimethyleneglycol 
• 126747-15-7 2-(4-carbamoylphenyl)-1,3,2-dioxaborinane 

Downstream Products

• 126747-14-6 4-cyanophenylboronic acid 
• 1591-30-6 (1,1'-biphenyl)-4,4'-dicarbonitrile 

Relevant articles and documents

Ruthenium(0)-catalyzed sp3 C-H bond arylation of benzylic amines using arylboronates

A Ru-catalyzed direct arylation of benzylic sp3 carbons of acyclic amines with arylboronates is reported. This highly regioselective and efficient transformation can be performed with various combinations of N-(2-pyridyl) substituted benzylamines and arylboronates. Substitution of the pyridine directing group in the 3-position proved to be crucial in order to achieve high arylation yields. Furthermore, the pyridine directing group can be removed in high yields via a two-step protocol.