152892-83-6

Basic information

• Product Name: (2S,4S)-2-benzyl 1-tert-butyl 4-(benzyloxy)pyrrolidine-1,2-dicarboxylate
• Synonyms: (2S,4S)-2-benzyl 1-tert-butyl 4-(benzyloxy)pyrrolidine-1,2-dicarboxylate
• CAS NO: 152892-83-6
• Molecular Weight: 411.498
• Mol File: 152892-83-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (2S,4S)-2-benzyl 1-tert-butyl 4-(benzyloxy)pyrrolidine-1,2-dicarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,4S)-2-benzyl 1-tert-butyl 4-(benzyloxy)pyrrolidine-1,2-dicarboxylate(152892-83-6)
• EPA Substance Registry System: (2S,4S)-2-benzyl 1-tert-butyl 4-(benzyloxy)pyrrolidine-1,2-dicarboxylate(152892-83-6)

Safety Data

• Hazardous Substances Data: 152892-83-6(Hazardous Substances Data)

Upstream product

• 100-39-0 benzyl bromide 
• 87691-27-8 N-tert-butoxycarbonyl-L-cis-4-hydroxyproline 
• 77-92-9 citric acid 

Downstream Products

• 40350-83-2 (2S,4S)-4-(benzyloxy)-1-(tert-butoxycarbonyl)pyrrolidine-2-carboxylic acid 

Relevant articles and documents

ARGINASE INHIBITORS AND METHODS OF USE THEREOF

Disclosed are compounds of formula (Ia) or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising compounds of formula (Ia) and methods of using the same for treating cancer or a respiratory inflammatory disease and inhibiting arginase, wherein R1 is -NHR1a; R1a is -H or -C(O)CH(R1b)NHR1c; and R1b is selected from -H, -(C1-C4 ) alkyl and CH2OR1d and R1cis -H; or R1b and R1c, together with the atom to which they are attached, form a 5-membered heterocyclic ring; and R1d is H or -CH3.