152897-85-3

Basic information

• Product Name: 2,4-Dimethyl-6-(phenylamino)-1H,2H-phthalazino<2',1':3,4>pyrimido<4,5-d>pyrimidine-1,3(2H,4H)-dione
• Synonyms: 2,4-Dimethyl-6-(phenylamino)-1H,2H-phthalazino<2',1':3,4>pyrimido<4,5-d>pyrimidine-1,3(2H,4H)-dione
• CAS NO: 152897-85-3
• Molecular Weight: 386.413
• Mol File: 152897-85-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2,4-Dimethyl-6-(phenylamino)-1H,2H-phthalazino<2',1':3,4>pyrimido<4,5-d>pyrimidine-1,3(2H,4H)-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-Dimethyl-6-(phenylamino)-1H,2H-phthalazino<2',1':3,4>pyrimido<4,5-d>pyrimidine-1,3(2H,4H)-dione(152897-85-3)
• EPA Substance Registry System: 2,4-Dimethyl-6-(phenylamino)-1H,2H-phthalazino<2',1':3,4>pyrimido<4,5-d>pyrimidine-1,3(2H,4H)-dione(152897-85-3)

Safety Data

• Hazardous Substances Data: 152897-85-3(Hazardous Substances Data)

Upstream product

• 253-52-1 PHTHALAZINE 
• 99747-54-3 1,3-dimethyl-2,4-dioxo-6-<(triphenylphosphoranylidene)amino>-1,2,3,4-tetrahydropyrimidine 
• 103-71-9 phenyl isocyanate 

Relevant articles and documents

Reactions of uracils. 21. Zwitterionic heteropolycyclic uracils by a novel three-component reaction: Iminophosphorane, isocyanate, heteroarene

The novel three-component reaction of (uracil-6-ylimino)phosphorane 1, isocyanate 2, and (substituted) pyridines gives, in a one-pot procedure, a variety of new pyrido[1',2':3,4]pyrimido[4,5-d]pyrimidines 3-11. The zwitterionic ground state of these new ring systems is i.a. established by means of solvatochromism, Hammett correlations, NMR, and X-ray analysis. Replacement of the pyridine by isoquinoline and phthalazine gives access to the novel ring systems pyrimido[4',5':4,5]pyrimido[6,1-a]isoquinoline and -phthalazine, which are formed as dihydro derivatives (14, 15) or as zwitterions (13, 17), depending on the reaction conditions. Oxidative cleavage of the phthalazine 15 in nitrobenzene affords the pyrimido[4,5-d]pyrimidines 16.