1529769-88-7

Basic information

• Product Name: 4-[3-nitro-5-(trifluoromethyl)phenyl]-1,4-thiazinane 1,1-dioxide
• Synonyms: 4-[3-nitro-5-(trifluoromethyl)phenyl]-1,4-thiazinane 1,1-dioxide
• CAS NO: 1529769-88-7
• Molecular Weight: 324.281
• Mol File: 1529769-88-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 4-[3-nitro-5-(trifluoromethyl)phenyl]-1,4-thiazinane 1,1-dioxide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[3-nitro-5-(trifluoromethyl)phenyl]-1,4-thiazinane 1,1-dioxide(1529769-88-7)
• EPA Substance Registry System: 4-[3-nitro-5-(trifluoromethyl)phenyl]-1,4-thiazinane 1,1-dioxide(1529769-88-7)

Safety Data

• Hazardous Substances Data: 1529769-88-7(Hazardous Substances Data)

Upstream product

• 630125-49-4 1-bromo-3-nitro-5-(trifluoromethyl)benzene 

Relevant articles and documents

NOVEL INHIBITORS OF MAP4K1

The invention relates to novel inhibitors of MAP4K1 (HPK1) useful for the treatment of diseases or disorders characterised by dysregulation of the signal transduction pathways associated with MAPK activation, including hyperproliferative diseases, diseases of immune system dysfunction, inflammatory disorders, neurological diseases, and cardiovascular diseases. The invention further relates to pharmaceutical compositions comprising the same and methods of treatment of said diseases and disorders. The inhibitors are of formula (I) wherein the definitions for A, D, E, F, R5, R6, R7, Z, ring Q, n, x and y are as given in the application.

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