153026-78-9

Basic information

• Product Name: 3-Thiophenemethanol, a-ethynyl-
• CAS NO: 153026-78-9
• Molecular Formula: C7H6OS
• Molecular Weight: 138.19
• Mol File: 153026-78-9.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: 3-Thiophenemethanol, a-ethynyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Thiophenemethanol, a-ethynyl-(153026-78-9)
• EPA Substance Registry System: 3-Thiophenemethanol, a-ethynyl-(153026-78-9)

Safety Data

• Hazardous Substances Data: 153026-78-9(Hazardous Substances Data)

Upstream product

• 498-62-4 3-thiophene carboxaldehyde 
• 65032-27-1 ethynylmagnesium chloride 
• 4301-14-8 acetylenemagnesium bromide 
• 849769-14-8 1-(thiophen-3-yl)-3-(trimethylsilyl)prop-2-yn-1-ol 

Downstream Products

• 275815-89-9 (E)-3-(4-nitropheny)-1-thiophen-3-yl-propenone 
• 1374430-61-1 2-oxocyclohexanecarboxylic acid 1-thiophen-3-ylprop-2-ynyl ester 
• 1609661-94-0 C₁₃H₉BrOS 
• 1609661-66-6 (1-(2-bromophenyl)-3-(thiophen-3-yl)propa-1,2-dien-1-yl)diphenylphosphine oxide 

Relevant articles and documents

Synthesis of (Z)-alkene-containing linear conjugated dienyl homoallylic alcohols by a palladium-catalyzed three-component reaction

A synthesis of (Z)-alkene-containing linear conjugated dienyl homoallylic alcohols by using a palladium-catalyzed three-component reaction has been developed. This method shows good functional-group compatibility and generality, with high diastereoselectivity. Additionally, in many cases, the present method controls the alkene stereochemistry of the newly formed C-C bond and overcomes the inherent preference for (E)-alkene formation, giving (Z, E)- and (Z, Z)-products.

Allenylic Carbonates in Enantioselective Iridium-Catalyzed Alkylations

An enantioconvergent C(sp3)-C(sp3) coupling between racemic allenylic electrophiles and alkylzinc reagents has been developed. An Ir/(phosphoramidite,olefin) catalyst provides access to highly enantioenriched allenylic substitution p

One-Pot Cannizzaro Cascade Synthesis of ortho-Fused Cycloocta-2,5-dien-1-ones from 2-Bromo(hetero)aryl Aldehydes

An intramolecular Cannizzaro-type hydride transfer to an in situ prepared allene enables the synthesis of ortho-fused 4-substituted cycloocta-2,5-dien-1-ones with unprecedented technical ease for an eight-ring carboannulation. Various derivatives could be obtained from commercially available (hetero)aryl aldehydes, trimethylsilylacetylene, and simple propargyl chlorides in good yields. A cascade process that is triggered by an intramolecular Cannizzaro-type hydride transfer to an in situ prepared allene leads to the formation of 4-substituted cycloocta-2,5-dien-1-ones. Various derivatives could be obtained from commercially available (hetero)aryl aldehydes, trimethylsilylacetylene, and simple propargyl chlorides in good yields.