15311-10-1

Basic information

• Product Name: 3-(5-phenyl-1,3,4-thiadiazol-2-yl)pyridine
• CAS NO: 15311-10-1
• Molecular Formula: C₁₃H₉N₃S
• Molecular Weight: 239.2957
• Mol File: 15311-10-1.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 431°C at 760 mmHg
• Flash Point: 208.3°C
• Density: 1.265g/cm³
• Vapor Pressure: 3.13E-07mmHg at 25°C
• Refractive Index: 1.639
• CAS DataBase Reference: 3-(5-phenyl-1,3,4-thiadiazol-2-yl)pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(5-phenyl-1,3,4-thiadiazol-2-yl)pyridine(15311-10-1)
• EPA Substance Registry System: 3-(5-phenyl-1,3,4-thiadiazol-2-yl)pyridine(15311-10-1)

Safety Data

• Hazardous Substances Data: 15311-10-1(Hazardous Substances Data)

Upstream product

• 20605-40-7 thiobenzoylhydrazine 
• 53830-52-7 nicotinic acid N-methylthioamide 
• 4621-66-3 thionicotinamide 
• 32252-82-7 1-chloro-1,4-diphenyl-2,3-diazabutadiene 
• 56352-76-2 benzoic acid(pyridine-3-carbonyl)hydrazide 
• 114-33-0 N-Methylnicotinamide 
• 942-91-6 Carboxymethyl dithiobenzoate 
• 626-55-1 3-Bromopyridine 
• 4291-14-9 phenyl-1,3,4-thiadiazole 

Relevant articles and documents

Carboxyboronate: A Versatile C1 Building Block

The synthesis and applications of carboxy-MIDA-boronate, a novel C1 building block, are described. This molecule is accessible via a ruthenium tetraoxide-mediated cleavage of commercially available ethynyl-MIDA-boronate. In the course of this study, carboxy-MIDA-boronate was found to possess ambident reactivity towards nucleophiles. Carboxylic acid derivatization produces a broad range of previously unknown carbamoyl-, oxycarbo- and thiocarboboronates. Carboxy-MIDA-boronate and its derivatives undergo condensations to access borylated heterocycles with boron at positions that are difficult to access using alternate methods. The resulting heterocycles participate in the Suzuki–Miyaura cross-coupling reaction, enabling entry into diverse bis(heteroaryl) motifs. The carbon monoxide-releasing capacity of carboxy-MIDA-boronate was also examined and applied in palladium-catalyzed carbonylation.

Synthesis of substituted 1,3,4-thiadiazoles using Lawesson's reagent

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Thiadiazoles and Thiadiazolines. Part 3. Synthesis of Triazol-3-yl-Δ2-1,3,4-thiadiazolines and a New Synthesis of Unsymmetrical 2,5-Di-substituted 1,3,4-Thiadiazoles

The reaction of 1-chloro-1,4-diphenyl-2,3-diazabutadiene (1) with 1-acetyl- and with 1-benzoyl-thiosemicarbazide yields initially the hydrochlorides of N2-acetyl- and N2-benzoyl-Δ2-1,3,4-thiadiazoline-4-carboxamide hydrazo