153182-61-7 Usage
Description
(4R,5S,6S,7R)-4,7-dibenzyl-1,3-bis(cyclohexylmethyl)-5,6-dihydroxy-1,3-diazepan-2-one is a complex organic compound characterized by its diazepan ring structure. It features four benzyl groups and two cyclohexylmethyl groups, along with two hydroxyl groups. As a dihydroxy-diazepan-2-one, the molecule contains a six-membered ring with two adjacent hydroxyl groups and a carbonyl group. This intricate molecular architecture suggests potential for diverse pharmacological activities, making it a compound of interest in medicinal chemistry and drug development.
Uses
Used in Pharmaceutical Industry:
(4R,5S,6S,7R)-4,7-dibenzyl-1,3-bis(cyclohexylmethyl)-5,6-dihydroxy-1,3-diazepan-2-one is used as a potential pharmaceutical candidate for various applications due to its complex structure and the presence of multiple functional groups that can interact with biological targets.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, (4R,5S,6S,7R)-4,7-dibenzyl-1,3-bis(cyclohexylmethyl)-5,6-dihydroxy-1,3-diazepan-2-one is used as a starting point for the development of new drugs. Its unique structural features may allow for the design of molecules with specific biological activities, targeting various diseases and conditions.
Used in Drug Delivery Systems:
Similar to other complex organic compounds, (4R,5S,6S,7R)-4,7-dibenzyl-1,3-bis(cyclohexylmethyl)-5,6-dihydroxy-1,3-diazepan-2-one could be utilized in the development of novel drug delivery systems. These systems may enhance the compound's bioavailability, targeting, and overall therapeutic efficacy.
Check Digit Verification of cas no
The CAS Registry Mumber 153182-61-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,3,1,8 and 2 respectively; the second part has 2 digits, 6 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 153182-61:
(8*1)+(7*5)+(6*3)+(5*1)+(4*8)+(3*2)+(2*6)+(1*1)=117
117 % 10 = 7
So 153182-61-7 is a valid CAS Registry Number.
InChI:InChI=1/C33H46N2O3/c36-31-29(21-25-13-5-1-6-14-25)34(23-27-17-9-3-10-18-27)33(38)35(24-28-19-11-4-12-20-28)30(32(31)37)22-26-15-7-2-8-16-26/h1-2,5-8,13-16,27-32,36-37H,3-4,9-12,17-24H2/t29-,30-,31+,32+/m1/s1
153182-61-7Relevant articles and documents
Cyclic HIV protease inhibitors: Synthesis, conformational analysis, P2/P2' structure-activity relationship, and molecular recognition of cyclic ureas
Lam, Patrick Y. S.,Ru, Yu,Jadhav, Prabhakar K.,Aldrich, Paul E.,DeLucca, George V.,Eyermann, Charles J.,Chang, Chong-Hwan,Emmett, George,Holler, Edward R.,Daneker, Wayne F.,Li, Liangzhu,Confalone, Pat N.,McHugh, Robert J.,Han, Qi,Li, Renhua,Markwalder, Jay A.,Seitz, Steven P.,Sharpe, Thomas R.,Bacheler, Lee T.,Rayner, Marlene M.,Klabe, Ronald M.,Shum, Linyee,Winslow, Dean L.,Kornhauser, David M.,Jackson, David A.,Erickson-Viitanen, Susan,Hodge, C. Nicholas
, p. 3514 - 3525 (2007/10/03)
High-resolution X-ray structures of the complexes of HIV-1 protease (HIV-1PR) with peptidomimetic inhibitors reveal the presence of a structural water molecule which is hydrogen bonded to both the mobile flaps of the enzyme and the two carbonyls flanking
