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153223-25-7

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153223-25-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 153223-25-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,3,2,2 and 3 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 153223-25:
(8*1)+(7*5)+(6*3)+(5*2)+(4*2)+(3*3)+(2*2)+(1*5)=97
97 % 10 = 7
So 153223-25-7 is a valid CAS Registry Number.

153223-25-7Relevant articles and documents

PHOSPHONATES - A NOVEL TYPE NUCLEOTIDE ANALOGS RELATED TO HPMPA. I. DERIVATIVES WITH L-arabino, D-arabino, 2-DEOXY-L-erythro AND 2-DEOXY-L-threo CONFIGURATION

Otmar, Miroslav,Rosenberg, Ivan,Masojidkova, Milena,Holy, Antonin

, p. 2159 - 2179 (2007/10/02)

phosphonates, a new type of nucleotide analogs with fixed HPMPA structure, have been prepared.The synthesis of compounds of L-arabino (IIa, IIb), D-arabino (XIVa, XIVb), 2-deoxy-L-erythro (IIIa, IIIb) and 2-deoxy-L-threo (IVa, IVb) configuration is based on the Michaelis-Arbuzov reaction of the fully protected methyl glycosides with triethyl phosphite and trimethylsilyl triflate which leads to anomeric mixture of diethyl (L-pentofuranosyl) phosphonates.The protected 5-O-tosyl derovatives react with sodium salt of adenine to give N9-substituted products which after total deprotection afford the title nucleotide analogs.The fixation of the partial structure of HPMPA to form five-membered ring leads to a significant decrease, or a total loss, of biological activity.

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