153248-46-5 Usage
Description
1-Hydroxymethyl-1-(tert-butoxycarbonylaminomethyl)cyclopropane, also known as [1-[(Boc-amino)methyl]cyclopropyl]methanol, is a chemical compound with a unique structure that features a cyclopropane ring, a hydroxymethyl group, and a tert-butoxycarbonylaminomethyl group. 1-Hydroxymethyl-1-(tert-butoxycarbonylaminomethyl)cyclopropane is characterized by its potential reactivity and versatility in chemical synthesis, making it a valuable intermediate in the preparation of various complex organic molecules.
Uses
Used in Pharmaceutical Industry:
1-Hydroxymethyl-1-(tert-butoxycarbonylaminomethyl)cyclopropane is used as a key reactant for the synthesis of imidazolylalkylamine compounds, which are of significant interest in the pharmaceutical industry. These imidazolylalkylamine compounds are specifically designed to inhibit human glutaminyl cyclase, an enzyme that plays a crucial role in the post-translational modification of proteins. Inhibition of this enzyme can have therapeutic implications in the treatment of various diseases and disorders related to protein misfolding and aggregation.
Used in Chemical Synthesis:
In the field of chemical synthesis, 1-Hydroxymethyl-1-(tert-butoxycarbonylaminomethyl)cyclopropane serves as an important building block for the creation of more complex organic molecules. Its unique structure allows for further functionalization and modification, making it a valuable asset in the development of new drugs, materials, and other specialty chemicals.
Check Digit Verification of cas no
The CAS Registry Mumber 153248-46-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,3,2,4 and 8 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 153248-46:
(8*1)+(7*5)+(6*3)+(5*2)+(4*4)+(3*8)+(2*4)+(1*6)=125
125 % 10 = 5
So 153248-46-5 is a valid CAS Registry Number.
153248-46-5Relevant articles and documents
TRICYCLIC COMPOUNDS AND THEIR USE
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Page/Page column 81, (2020/12/29)
Tricyclic compounds and their use are provided. More specifically, tricyclic compounds, pharmaceutical compositions containing them, methods for preparing them, and their use in therapy are also provided.
SGC STIMULATORS
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, (2014/09/29)
Compounds of Formulae (I') and (I) are described, which are useful as stimulators of sGC, particularly NO-independent, heme-dependent stimulators. These compounds are also useful for treating, preventing or managing various disorders that are herein disclosed.
ANTIBACTERIAL AMINOGLYCOSIDE ANALOGS
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Page/Page column 77-78, (2011/04/26)
Compounds having antibacterial activity are disclosed. The compounds have the following structure (I) including stereoisomers, pharmaceutically acceptable salts and prodrugs thereof, wherein Q1, Q2, Q5, R1, R2, R3, Z1 and Z2 are as defined herein. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.
