153253-42-0

Basic information

• Product Name: 2-[2-(2-azidoethoxy)ethoxy]ethyl (2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-(1->4)-2,3,6-tri-O-acetyl-β-D-glucopyranoside
• Synonyms: 2-[2-(2-azidoethoxy)ethoxy]ethyl (2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-(1->4)-2,3,6-tri-O-acetyl-β-D-glucopyranoside
• CAS NO: 153253-42-0
• Molecular Weight: 793.733
• Mol File: 153253-42-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-[2-(2-azidoethoxy)ethoxy]ethyl (2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-(1->4)-2,3,6-tri-O-acetyl-β-D-glucopyranoside(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[2-(2-azidoethoxy)ethoxy]ethyl (2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-(1->4)-2,3,6-tri-O-acetyl-β-D-glucopyranoside(153253-42-0)
• EPA Substance Registry System: 2-[2-(2-azidoethoxy)ethoxy]ethyl (2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-(1->4)-2,3,6-tri-O-acetyl-β-D-glucopyranoside(153253-42-0)

Safety Data

• Hazardous Substances Data: 153253-42-0(Hazardous Substances Data)

Upstream product

• 86520-52-7 2-[2-(2-azidoethoxy)ethoxy]ethanol 
• 92052-38-5 O-<2,3,6-tri-O-acetyl-4-O-(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-α,β-D-glucopyranosyl>trichloroacetimidate 
• 4753-07-5 2,3,6,2',3',4',6'-hepta-O-acetyl-lactosyl bromide 

Downstream Products

• 733051-82-6 8-phthalimido-3,6-dioxaoctyl 4-O-(β-D-galactooyranosyl)-β-D-glucopyranoside 

Relevant articles and documents

A glyco-gold nanoparticle based assay for α-2,8-polysialyltransferase from Neisseria meningitidis

We designed a novel strategy for sensitively detecting the activity of α-2,8-polysialyltransferase (PST) by a combination of ganglioside GD3 functionalized gold nanoparticles and inactive endosialidase. We anticipate that this new method will facilitate the search for PST inhibitors as well as for improved mutant forms of PST in directed evolution experiments. The Royal Society of Chemistry 2013.

Bacteria targeted by human natural antibodies using α-gal conjugated receptor-specific glycopolymers

Synthesis of polymerizable β-lactosyl, Galα1→3Gal and α-mannosyl acrylamide derivatives with either a hydrophobic aromatic spacer or a hydrophilic biocompatible oligoethoxyl spacer was accomplished. Radical terpolymerizations of β-lactosyl monomer, α-mannosyl monomer, and acrylamide were conducted in aqueous media with ammonium persulfate and N,N,N',N'-tetramethylethylenediamine as initiators. The resulting water soluble glycopolymers were further transformed efficiently by a recombinant α1→3 galactosyltransferase to afford mediators bearing Galα1→3Gal termini as xenoactive antigens and α-mannosyl termini as specific ligands for bacterial cells. The binding of the resulting multivalent glycopolymer to bacteria was tested by its ability to inhibit agglutination of yeast to E. coli. The binding of human natural anti-Gal antibodies to the α-Gal containing glycopolymers and a monovalent α-Gal-Man glycoconjugate was demonstrated by an ELISA inhibition assay. Copyright (C) 1999 Elsevier Science Ltd.