153277-33-9 Usage
Description
CBZ-S-PHENYL-L-CYSTEINE METHYL ESTER, also known as N-Carbobenzoxy-S-phenyl-L-cysteine methyl ester, is a chemical compound derived from α-amino acid derivatives. It is characterized by its unique structure, which allows for various chemical reactions and applications in different industries.
Uses
Used in Pharmaceutical Industry:
CBZ-S-PHENYL-L-CYSTEINE METHYL ESTER is used as an intermediate compound for the synthesis of various pharmaceutical products. Its unique structure enables it to participate in cross-Claisen condensation reactions with alkyl acetates, leading to the formation of γ-amino β-ketoesters. These γ-amino β-ketoesters are valuable building blocks in the development of new drugs and therapeutic agents.
Used in Chemical Synthesis:
In the field of organic chemistry, CBZ-S-PHENYL-L-CYSTEINE METHYL ESTER serves as a versatile reagent for the preparation of complex organic molecules. Its ability to undergo cross-Claisen condensation with alkyl acetates makes it a valuable tool for the synthesis of a wide range of compounds, including those with potential applications in various industries such as pharmaceuticals, agrochemicals, and materials science.
Check Digit Verification of cas no
The CAS Registry Mumber 153277-33-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,3,2,7 and 7 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 153277-33:
(8*1)+(7*5)+(6*3)+(5*2)+(4*7)+(3*7)+(2*3)+(1*3)=129
129 % 10 = 9
So 153277-33-9 is a valid CAS Registry Number.
InChI:InChI=1/C18H19NO4S/c1-22-17(20)16(13-24-15-10-6-3-7-11-15)19-18(21)23-12-14-8-4-2-5-9-14/h2-11,16H,12-13H2,1H3,(H,19,21)/t16-/m0/s1
153277-33-9Relevant articles and documents
Process for S-Aryl cysteine
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Example 8, (2008/06/13)
The present invention provides methods for preparing S-aryl cysteines in enantiomeric excess of greater than about 96%. Specifically, the present invention provides enantioselective methods for preparing S-aryl cysteines starting from cystine, cysteine or
Process for producing of cysteine derivatives
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, (2008/06/13)
PCT No. PCT/JP98/00101 Sec. 371 Date Apr. 22, 1999 Sec. 102(e) Date Apr. 22, 1999 PCT Filed Jan. 14, 1998 PCT Pub. No. WO98/30538 PCT Pub. Date Jul. 16, 1998This invention relates to a method comprising reacting an amino acid derivative of the following general formula (I); (wherein R1 represents an amino-protective group; R0 represents hydrogen or, taken together with R1, represents an amino-protecting group; R2 represents a carboxy-protecting group; X represents a leaving group) with a thiol compound of the following general formula (II):R3SH(II)(wherein R3 represents an alkyl group of 1 to 7 carbon atoms, an aryl group of 6 to 10 carbon atoms, or an aralkyl group of 7 to 10 carbon atoms) to give a cysteine derivative of the following general formula (III): (wherein R0, R1, R2, and R3 are as defined above), wherein the reaction is conducted in the presence of a base and water in an organic reaction solvent.
A total synthesis of (-)-slaframine from (+)-cis-(2R,3S)-3-hydroxyproline
Knight,Sibley
, p. 6607 - 6610 (2007/10/02)
A total synthesis of the naturally occurring indolizidine (-)-Slaframine 4 has been achieved, starting from the cis-3-hydroxyproline derivative 1, in which a key step is a Julia olefination reaction using the dianion derived from the β-aminosulfone 5.