153390-61-5

Basic information

• Product Name: 1-(3-TrifluoroMethylphenyl)-1-MethylethylaMine
• Synonyms: 1-(3-TrifluoroMethylphenyl)-1-MethylethylaMine;2-[3-(Trifluoromethyl)phenyl]propan-2-amine hydrochloride;2-[3-(TRIFLUOROMETHYL)PHENYL]PROPAN-2-AMINE;1-methyl-1-[3-(trifluoromethyl)phenyl]ethylamine hydrochloride
• CAS NO: 153390-61-5
• Molecular Formula: C₁₀H₁₂F₃N
• Molecular Weight: 239.6651296
• Mol File: 153390-61-5.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 196.8±35.0 °C(Predicted)
• Appearance: /
• Density: 1.149±0.06 g/cm3(Predicted)
• PKA: 9.04±0.10(Predicted)
• CAS DataBase Reference: 1-(3-TrifluoroMethylphenyl)-1-MethylethylaMine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(3-TrifluoroMethylphenyl)-1-MethylethylaMine(153390-61-5)
• EPA Substance Registry System: 1-(3-TrifluoroMethylphenyl)-1-MethylethylaMine(153390-61-5)

Safety Data

• Hazardous Substances Data: 153390-61-5(Hazardous Substances Data)

Usage

General Description

1-(3-TrifluoroMethylphenyl)-1-MethylethylaMine is a chemical compound that belongs to the class of aromatic amines. It is also known by its chemical formula C10H12F3N. 1-(3-TrifluoroMethylphenyl)-1-MethylethylaMine is commonly used as a building block in the synthesis of pharmaceuticals and agrochemicals. It is a colorless liquid at room temperature and is soluble in organic solvents like ethanol and acetone. It is important to handle this chemical with care as it can be harmful if it comes into contact with skin or if it is inhaled.

Upstream product

• 368-77-4 3-trifluoromethylbenzonitrile 
• 917-54-4 methyllithium 

Downstream Products

• 959133-22-3 2-[4-(3-fluorobenzyl)-3-(2-hydroxyphenyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-N-[1-methyl-1-(3-trifluoromethyl-phenyl)ethyl]-acetamide 
• 959139-24-3 2-chloro-N-{1-methyl-1-[3-(trifluoromethyl)phenyl]ethyl}acetamide 
• 959131-42-1 2-[3-(4-chlorophenyl)-4-cyclopropyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-N-{1-methyl-1-[3-(trifluoromethyl)phenyl]ethyl}acetamide 
• 959133-15-4 2-[3-(5-chlorothiophen-2-yl)-4-(2-fluorobenzyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-N-[1-methyl-1-(3-trifluoromethyl-phenyl)ethyl]-acetamide 

Relevant articles and documents

Substituted Arylimidazolone and Triazolone as Inhibitors of Vasopressin Receptors

The present application relates to novel, substituted 4-arylimidazol-2-ones and 5-aryl-1,2,4-triazolones, processes for the production thereof, the use thereof alone or in combinations for the treatment and/or prevention of diseases and the use thereof for the production of medicaments for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of cardiovascular diseases.

TRICYCLIC INDOLE DERIVATIVES AND THEIR USE IN THE TREATMENT OF ALZHEIMER’S DISEASE

The present invention relates to novel hydroxyethylamine compounds having Asp2 (β-secretase, BACE1 or Memapsin) inhibitory activity, processes for their preparation, to compositions containing them and to their use in the treatment of diseases characterised by elevated β- amyloid levels or β-amyloid deposits, particularly Alzheimer's disease.