153413-65-1Relevant articles and documents
Synthesis of phosphorofluoridates and phosphorofluoridothioates via the phosphoramidite approach
Dabkowski, Wojciech,Tworowska, Izabela
, p. 866 - 874 (2005)
We present a very efficient synthetic procedure leading to the phosphorofluoridates RO-P(O)(OH)F 1 or phosphorofluoridothioates RO-P(S)(OH)F 2, which is based on the intermediary of fluorophosphoramidites (RO)P(F)N iPr2 5 [R = 9-(hyd
Highly selective O-phosphitylation of amino alcohols using P IIIreagents containing 4-nitro and 2,4-dinitro aryloxy leaving groups
Dabkowski, Wojciech,Ozarek, Alfred,Tworowska, Izabela
, p. 1396 - 1399 (2007/10/03)
A method for direct highly O-selective phosphitylation of amino alcohols by reagents containing a 4-nitrophenoxy or 2,4 dinitrophenoxy leaving group has been developed. This method provides mild reaction conditions to access O-phosphitylated amino alcohol
Novel phosphitylating reagents containing a phosphorus-fluorine bond and their application in efficient synthesis of phosphorofluoridates and phosphorofluoridothionates
Dabkowski, Wojciech,Tworowska, Izabela
, p. 2462 - 2469 (2007/10/03)
Novel phosphitylating reagents containing a P-F bond are obtained in excellent yield from commercial materials. They react with alcohols at 20 °C in neutral solvents in the presence of tetrazole, chlorotrimethylsilane or benzoyl chloride to give the inter