153493-52-8 Usage
General Description
1,1-Cyclopropanedimethanol cyclic sulfite is a chemical compound used as a reagent in organic synthesis. It is a cyclic sulfite derivative of 1,1-cyclopropanedimethanol, and is commonly used as a protecting group for alcohols in organic chemistry reactions. 1,1-Cyclopropanedimethanol cyclic sulfite is stable and can be easily handled in the laboratory, making it a useful reagent for various synthetic transformations. Its cyclic structure imparts unique reactivity and selectivity in reactions, making it a valuable tool for organic chemists in the synthesis of complex molecules. Additionally, the cyclic sulfite moiety can be easily removed under mild conditions, making it a versatile and practical choice for alcohol protection in organic synthesis.
Check Digit Verification of cas no
The CAS Registry Mumber 153493-52-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,3,4,9 and 3 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 153493-52:
(8*1)+(7*5)+(6*3)+(5*4)+(4*9)+(3*3)+(2*5)+(1*2)=138
138 % 10 = 8
So 153493-52-8 is a valid CAS Registry Number.
153493-52-8Relevant articles and documents
5 - azaspiro [2.4] heptane - 6 - carboxylic acid derivatives of the synthesis method (by machine translation)
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Paragraph 0045-0047, (2017/08/25)
The present invention provides a (5S) - 5 - azaspiro [2.4] heptane - 6 - carboxylic acid derivatives of the synthetic method, in order to 1, 1 - cyclopropane dicarboxylic alcohol as the starting material, the reaction with thionyl chloride, is oxidized and get sulfonic acid ester compound, then with glycine methyl ester imine under the action of the tertiary butyl alcohol potassium condensation, again through the system acidic, alkaline methylsulphonyl complete hydrolysis, cyclization, amino protection of the racemic product, finally split to obtain the finished product, the total yield up to 30% or more, the reaction route step is short, reagent used in the security, the operation is simple, of low cost, high yield, suitable for industrial production. (by machine translation)
