153511-19-4

Basic information

• Product Name: S-(2-formylphenyl) N,N-dimethylthiocarbamate
• Synonyms: S-(2-formylphenyl) N,N-dimethylthiocarbamate
• CAS NO: 153511-19-4
• Molecular Weight: 209.269
• Mol File: 153511-19-4.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: S-(2-formylphenyl) N,N-dimethylthiocarbamate(CAS DataBase Reference)
• NIST Chemistry Reference: S-(2-formylphenyl) N,N-dimethylthiocarbamate(153511-19-4)
• EPA Substance Registry System: S-(2-formylphenyl) N,N-dimethylthiocarbamate(153511-19-4)

Safety Data

• Hazardous Substances Data: 153511-19-4(Hazardous Substances Data)

Upstream product

• 90-02-8 salicylaldehyde 
• 89-95-2 2-methyl-benzyl alcohol 

Downstream Products

• 1342865-18-2 tris[2-(N,N-dimethylthiocarbamoyl)benzyl]amine 
• 24852-71-9 2-[(phenylmethyl)thio]benzaldehyde 
• 1087009-21-9 2-(1,1-dioxo-2-phenyl-2,3-dihydro-1H-benzo[b]thiophen-3-yl)-N-hydroxyacetamide 
• 1087010-13-6 2-(1,1-dioxo-2-phenyl-2,3-dihydro-1H-benzo[b]thiophen-3-yl)acetic acid 
• 1087010-09-0 (E)-3-(2-phenylmethanesulfonylphenyl)acrylic acid methyl ester 
• 1087010-11-4 2-(1,1-dioxo-2-phenyl-2,3-dihydro-1H-benzo[b]thiophen-3-yl)acetic acid methyl ester 
• 854280-52-7 methyl (E)-3-(2-benzylsulfanylphenyl)acrylate 

Relevant articles and documents

Conformational Effects of [Ni2(μ-ArS)2] Cores on Their Electrocatalytic Activity

Two nickel complexes supported by tridentate NS2 ligands, [Ni2(κ-N,S,S,S′-NPh{CH2(MeC6H2R′)S}2)2] (1; R′=3,5-(CF3)2C6H3) and [Ni2(κ-N,S,S,S′-NiBu{CH2C6H4S}2)2] (2), were prepared as bioinspired models of the active site of [NiFe] hydrogenases. The solid-state structure of 1 reveals that the [Ni2(μ-ArS)2] core is bent, with the planes of the nickel centers at a hinge angle of 81.3(5)°, whereas 2 shows a coplanar arrangement between both nickel(II) ions in the dimeric structure. Complex 1 electrocatalyzes proton reduction from CF3COOH at ?1.93 (overpotential of 1.04 V, with icat/ip≈21.8) and ?1.47 V (overpotential of 580 mV, with icat/ip≈5.9) versus the ferrocene/ferrocenium redox couple. The electrochemical behavior of 1 relative to that of 2 may be related to the bent [Ni2(μ-ArS)2] core, which allows proximity of the two Ni???Ni centers at 2.730(8) ?; thus possibly favoring H+ reduction. In contrast, the planar [Ni2(μ-ArS)2] core of 2 results in a Ni???Ni distance of 3.364(4) ? and is unstable in the presence of acid.

BICYCLOSULFONYL ACID (BCSA) COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS

This invention pertains generally to the field of therapeutic compounds, and more particularly, to certain bicyclosulfonyl acid (BCSA) compounds which act as inhibitors of Tumour Necrosis Factor-α Converting Enzyme (TACE). The compounds are useful in the