1536-02-3

Basic information

• Product Name: 1,4-Pentadien-3-ol, 1,5-diphenyl-3-(trifluoromethyl)-
• CAS NO: 1536-02-3
• Molecular Formula: C18H15F3O
• Molecular Weight: 304.312
• Mol File: 1536-02-3.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1,4-Pentadien-3-ol, 1,5-diphenyl-3-(trifluoromethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4-Pentadien-3-ol, 1,5-diphenyl-3-(trifluoromethyl)-(1536-02-3)
• EPA Substance Registry System: 1,4-Pentadien-3-ol, 1,5-diphenyl-3-(trifluoromethyl)-(1536-02-3)

Safety Data

• Hazardous Substances Data: 1536-02-3(Hazardous Substances Data)

Usage

Physical state

Colorless liquid

Odor

Fruity

Uses

a. Flavor and fragrance ingredient in consumer products
b. Production of polymers and resins
c. Organic synthesis reactions

Safety precautions

a. May be harmful if swallowed
b. May be harmful if inhaled
c. May cause skin irritation
d. May cause eye and respiratory system irritation

Handling procedures

Proper safety precautions should be followed when working with this compound.

Upstream product

• 76-05-1 trifluoroacetic acid 
• 75-46-7 trifluoromethan 
• 1586-73-8 tris(trimethylsilyl)amine 
• 35225-79-7 dibenzylideneacetone 
• 208331-51-5 (E,E)-3-trifluoromethyl-3-trimethylsilyloxy-1,5-diphenyl-1,4-pentadiene 
• 538-58-9 1,5-diphenyl-1,4-pentadiene-3-one 
• 100-52-7 benzaldehyde 

Downstream Products

• 1459697-04-1 (4-(trifluoromethyl)cyclopenta-1,3-diene-1,2-diyl)dibenzene 

Relevant articles and documents

Efficient synthesis of trifluoromethylated cyclopentadienes/fulvenes/ norbornenes from divinyl ketones

The synthetic methods of trifluoromethylated cyclopentadienes/fulvenes/ norbornenes have been developed using 3-CF3-1,4-dien-3-ols as the synthons, which can be easily prepared by the regiospecific 1,2-addition of the Ruppert-Prakash reagent (TMSCF3) to divinyl ketones. All the reactions are carried out under mild, metal-free conditions to afford the corresponding products in high to excellent yields.

Trifluoroacetamides from amino alcohols as nucleophilic trifluoromethylating reagents

Both non-enolizable and enolizable carbonyl compounds underwent nucleophilic trifluoromethylation by a new family of cheap and efficient trifluoroacetamide reagents derived from vic-amino alcohols (see picture). From an ecological and an economic viewpoint these represent a promising alternative to other known trifluoromethylation reagents.