153625-24-2

Basic information

• Product Name: 4-amino-3,5-bis(propan-2-yl)benzonitrile
• Synonyms: 4-amino-3,5-bis(propan-2-yl)benzonitrile
• CAS NO: 153625-24-2
• Molecular Weight: 202.299
• Mol File: 153625-24-2.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: 4-amino-3,5-bis(propan-2-yl)benzonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 4-amino-3,5-bis(propan-2-yl)benzonitrile(153625-24-2)
• EPA Substance Registry System: 4-amino-3,5-bis(propan-2-yl)benzonitrile(153625-24-2)

Safety Data

• Hazardous Substances Data: 153625-24-2(Hazardous Substances Data)

Upstream product

• 58633-04-8 3,5-dibromo-4-aminobenzonitrile 
• 873-74-5 4-Aminobenzonitrile 
• 80058-84-0 4-bromo-2,6-diisopropylaniline 
• 140411-20-7 4-iodo-2,6-diisopropylaniline 
• 24544-04-5 2,6-diisopropylbenzenamine 
• 557-21-1 zinc(II) cyanide 
• 50522-40-2 2,6-diisopropylaniline hydrochloric acid salt 
• 544-92-3 copper(I) cyanide 

Relevant articles and documents

SULFONIMIDAMIDE COMPOUNDS AS NLRP3 MODULATORS

Described herein are compounds of Formula (I), Formula (I-A), and Formula (I-B), solvates thereof, tautomers thereof, and pharmaceutically acceptable salts of the foregoing, Further described herein are methods of inhibiting NLRP3 using said compounds, and methods of and compositions useful in treating NLRP3-dependent disorders.

AGENT FOR REACTING WITH ACROLEIN, AND USE THEREOF AND NOVEL COMPOUND

PROBLEM TO BE SOLVED: To provide a reaction agent reacting with acrolein for detecting acrolein generated in a cell in a disease related to oxidative stress such as cancer, Alzheimer's and cerebral infarction. SOLUTION: There is provided a compound having a chemical structure represented by formula (1), wherein R1 and R2 each independently represents a hydrogen atom, a halogen atom, or an alkyl group having 1 to 5 carbon atoms which may be substituted with at least one halogen atom, with the proviso that at least one of R1 and R2 is an alkyl group having 1 to 5 carbon atoms; n is an integer of 1 or more and 5 or less; and * is a binding site with a rhodamine-based dye such as 5-carboxytetramethyl rhodamine or 6-carboxytetramethyl rhodamine or derivatives thereof. SELECTED DRAWING: None COPYRIGHT: (C)2020,JPO&INPIT

NLRP MODULATORS

In one aspect, compounds of Formula AA, or a pharmaceutically acceptable salt thereof, are featured: or a pharmaceutically acceptable salt thereof, wherein the variables shown in Formula A can be as defined anywhere herein, useful to treat connected to the modulation of NRLP3.