153652-71-2 Usage
Description
(4S,5R)-2,2-Dimethyl-4-phenyl-oxazolidine-3,5-dicarboxylic acid 3-tert-butyl ester 5-methyl ester is a complex organic compound characterized by its unique molecular structure. It is an intermediate in the synthesis of various pharmaceutical compounds and has potential applications in the medical field due to its ability to be used in the preparation of specific drug derivatives.
Uses
Used in Pharmaceutical Industry:
(4S,5R)-2,2-Dimethyl-4-phenyl-oxazolidine-3,5-dicarboxylic acid 3-tert-butyl ester 5-methyl ester is used as an intermediate for the synthesis of (4R,5S)-2,2-Dimethyl-4-phenyl-3,5-oxazolidinedicarboxylic Acid 3-(1,1-Dimethylethyl) Ester (O846295). (4S,5R)-2,2-Dimethyl-4-phenyl-oxazolidine-3,5-dicarboxylic acid 3-tert-butyl ester 5-methyl ester is a reagent for preparing 1,8-naphthyridine-3-carboxamide derivatives, which possess anticancer and anti-inflammatory activities.
Additionally, (4S,5R)-2,2-Dimethyl-4-phenyl-oxazolidine-3,5-dicarboxylic acid 3-tert-butyl ester 5-methyl ester can be used to synthesize taxol derivatives, which are known for their medical applications, particularly in the treatment of cancer.
Check Digit Verification of cas no
The CAS Registry Mumber 153652-71-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,3,6,5 and 2 respectively; the second part has 2 digits, 7 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 153652-71:
(8*1)+(7*5)+(6*3)+(5*6)+(4*5)+(3*2)+(2*7)+(1*1)=132
132 % 10 = 2
So 153652-71-2 is a valid CAS Registry Number.
153652-71-2Relevant articles and documents
New approaches to the asymmetric synthesis of dipeptide isosteres via β-Lactam Synthon Method
Ojima, Iwao,Wang, Hong,Wang, Tao,Ng, Edward W.
, p. 923 - 926 (2007/10/03)
New and efficient synthetic routes to dipeptide isosteres with high enantiomeric purity, e.g., hydroxyethylene, dihydroxyethylene and hydroxyethylamine isosteres, have been developed via oxiranes 6 and formyloxazolines 13 derived from N-t-Boc-β-lactams 4.
Synthetic application of chiral 4-methoxy-2-oxazolidinone synthons to 2-amino alcohols of biological interest
Ishizuka, Tadao,Morooka, Kohei,Ishibuchi, Seigo,Kunieda, Takehisa
, p. 837 - 848 (2007/10/03)
The versatility as chiral synthons of (4S, 5S)- and (4R, 5R)-5-allyl-4-methoxy-2-oxazolidinones, readily obtainable from 3-[(1S)-2-exo-alkoxy-1-apocamphanecarbonyl]-2-oxazolone, is demonstrated by the facile stereospecific conversions to (2R, 3S)-3-amino-2-hydroxy-3-phenylpentanoic acid, (2R, 3R, 5E, 7E)-2-amino-5,7-tetradecadien-3-ol and (2S, 3R)-dihydrosphingosine.
