153805-69-7

Basic information

• Product Name: (Z)-4-bromo-3-(4-methoxyphenyl)-2-butenoic acid ethyl ester
• Synonyms: (Z)-4-bromo-3-(4-methoxyphenyl)-2-butenoic acid ethyl ester
• CAS NO: 153805-69-7
• Molecular Weight: 299.164
• Mol File: 153805-69-7.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: (Z)-4-bromo-3-(4-methoxyphenyl)-2-butenoic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-4-bromo-3-(4-methoxyphenyl)-2-butenoic acid ethyl ester(153805-69-7)
• EPA Substance Registry System: (Z)-4-bromo-3-(4-methoxyphenyl)-2-butenoic acid ethyl ester(153805-69-7)

Safety Data

• Hazardous Substances Data: 153805-69-7(Hazardous Substances Data)

Upstream product

• 108454-55-3 3-(4-methoxyphenyl)-2-butenoic acid ethyl ester 
• 100-06-1 1-(4-methoxyphenyl)ethanone 
• 623-70-1 ethyl (E)-crotonate 
• 5720-07-0 4-methoxyphenylboronic acid 
• 7706-82-3 (E)-ethyl 3-(4-methoxyphenyl)but-2-enoate 

Downstream Products

• 894421-60-4 (Z)-ethyl 4-azido-3-(4-methoxyphenyl)but-2-enoate 

Relevant articles and documents

Rh-catalyzed asymmetric hydrogenation of γ-phthalimido-substituted α,β-unsaturated carboxylic acid esters: An efficient enantioselective synthesis of β-aryl-γ-amino acids

(Chemical Equation Presented) A series of chiral β-aryl-γ-amino acid ester derivatives were synthesized in high enantioselectivities (93-97% ee) via the Rh-catalyzed asymmetric hydrogenation of γ-phthalimido-α, β-unsaturated carboxylic acid esters using highly modular chiral BoPhoz-type phosphine-aminophosphine ligands. The method has been applied successfully to the synthesis of several chiral pharmaceuticals including (R)-baclofen and (R)-rolipram with high enantioselectivities.

Synthesis, X-ray crystal structure and optical properties of novel 2-aryl-3-ethoxycarbonyl-4-phenylpyrido[1,2-a]benzimidazoles

A series of novel 2-aryl-3-ethoxycarbonyl-4-phenylpyrido[1,2-a] benzimidazole derivatives were synthesized by the tandem reaction of 2-benzoyl benzimidazole and (Z)-ethyl 4-bromo-3-arylbut-2-enoate in the presence of potassium carbonate. The compounds were characterized using IR, 1H-NMR, 13C-NMR, HRMS and the structure of 6f was further determined by X-ray crystallography. Both absorption and fluorescence spectra characteristics of the compounds were investigated in acetonitrile and dichloromethane. The results showed that the absorption maxima of the compounds varied from 220 to 284 nm, depending on the structure of 2-aryl group. The fluorescence results revealed that these compounds exhibited blue-green fluorescence (463-475 nm) in dilute solutions and showed acceptable fluorescence quantum yields (PL = 0.13-0.73) in dichloromethane. Copyright