153877-53-3

Basic information

• Product Name: Benzenemethanol, 2-fluoro-a-(4-fluorophenyl)-
• CAS NO: 153877-53-3
• Molecular Formula: C13H10F2O
• Molecular Weight: 220.219
• Mol File: 153877-53-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Benzenemethanol, 2-fluoro-a-(4-fluorophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenemethanol, 2-fluoro-a-(4-fluorophenyl)-(153877-53-3)
• EPA Substance Registry System: Benzenemethanol, 2-fluoro-a-(4-fluorophenyl)-(153877-53-3)

Safety Data

• Hazardous Substances Data: 153877-53-3(Hazardous Substances Data)

Upstream product

• 342-25-6 2,4'-difluorobenzophenone 

Downstream Products

• 508211-26-5 methyl 2-[(2-fluorophenyl)(4-fluorophenyl)methoxy]-5-nitrobenzoate 
• 190444-06-5 C₁₆H₁₅ClF₂O 

Relevant articles and documents

Design, synthesis, and molecular docking study of new piperazine derivative as potential antimicrobial agents

Herein, we describe the successful design and synthesis of seventeen new 1,4-diazinanes, compounds commonly known as piperazines. This group of piperazine derivatives (3a-q) were fully characterized by 1H NMR, 13C NMR, FT-IR, and LCMS spectral techniques. The molecular structure of piperazine derivative (3h) was further established by single crystal X-ray diffraction analysis. All reported compounds were evaluated for their antibacterial and antifungal potential against five bacterial (Staphylococcus aureus, Escherichia coli, Klebsiella pneumoniae, Acinetobacter baumannii, and Pseudomonas aeruginosa) and two fungal strains (Candida albicans and Cryptococcus neoformans). The complete bacterial screening results are provided. As documented, piperazine derivative 3e performed the best against these bacteria. Additionally, data obtained during molecular docking studies are very encouraging with respect to potential utilization of these compounds to help overcome microbe resistance to pharmaceutical drugs, as explicitly noted in this manuscript.