153936-30-2Relevant articles and documents
Synthesis of novel 2,4-diarylchromans
Srivastava, Vandana,Ray, Suprabhat,Singh, M M
, p. 569 - 571 (2007/10/02)
Synthesis of the title compounds has been achieved by Grignard reaction on 7-methoxyflavone (1) with appropriate aryl halides and subsequent hydrogenation. 4-(p-Hydroxyphenyl)-7-methoxy-2-phenylchroman (6), thus prepared, is converted into the corresponding alkyl ethers (7a,b) and esters (7c,d).None of the compounds shows estrogenic, antiestrogenic or antifertility activity.