153953-01-6

Basic information

• Product Name: N-(4-amino-2-chloro-3-pyridyl)pentanamide
• Synonyms: N-(4-amino-2-chloro-3-pyridyl)pentanamide
• CAS NO: 153953-01-6
• Molecular Weight: 227.694
• Mol File: 153953-01-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-(4-amino-2-chloro-3-pyridyl)pentanamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-amino-2-chloro-3-pyridyl)pentanamide(153953-01-6)
• EPA Substance Registry System: N-(4-amino-2-chloro-3-pyridyl)pentanamide(153953-01-6)

Safety Data

• Hazardous Substances Data: 153953-01-6(Hazardous Substances Data)

Upstream product

• 39217-08-8 2-chloropyridine-3,4-diamine 
• 2082-59-9 pentanoic anhydride 
• 497-19-8 sodium carbonate 

Downstream Products

• 156222-03-6 2-butyl-4,5-dihydro-4-oxo-3-[2'-(tetrazol-5-yl)-biphenyl-4-ylmethyl]-5-(o-ethoxycarbonyl-benzyl)-3H-imidazo[4,5-c]-pyridine 
• 145047-27-4 2-Butyl-5-(2-nitro-benzyl)-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-3,5-dihydro-imidazo[4,5-c]pyridin-4-one 
• 156222-09-2 2-{2-Butyl-4-oxo-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-3,4-dihydro-imidazo[4,5-c]pyridin-5-yl}-N,N-diethyl-acetamide 
• 156221-84-0 2-<<2-butyl-3-<(2'-cyano-4-biphenylyl)methyl>-4,5-dihydro-4-oxo-3H-imidazo<4,5-c>pyridin-5-yl>methyl>benzoic acid, ethyl ester 
• 156221-96-4 4'-<<2-butyl-4,5-dihydro-5-<(N-methyl-N-phenylcarbamoyl)-methyl>-4-oxo-3H-imidazo<4,5-c>pyridin-3-yl>methyl>biphenyl-2-carbonitrile 
• 145047-08-1 4'-<(2-butyl-4,5-dihydro-5-(2-nitrobenzyl)-4-oxo-3H-imidazo<4,5-c>pyridin-3-yl)methyl>biphenyl-2-carbonitrile 
• 156221-95-3 4'-<<2-butyl-4,5-dihydro-5-<(2-oxo-2-pyrrolidino)ethyl>-4-oxo-3H-imidazo<4,5-c>pyridin-3-yl>methyl>biphenyl-2-carbonitrile 

Relevant articles and documents

Process for the preparation of imidazopyridines

The invention relates to a novel process for the preparation of imidazopyridines of formula I: STR1 in which R is an alkyl having 1-6 C atoms, characterized in that 3,4-diamino-2-chloropyridine (II) is reacted with an acid anhydride of the formula RCO--O--COR 40 (III), in which R is as defined and R' is R or can be another aliphatic or aromatic radical, to give a 4-amino-2-chloro-3-R-CO-aminopyridine (IV), this is converted with 4'-bromomethyl-2-cyanobiphenyl (V), in the presence of an alkali metal alcoholate in an inert solvent, to a 4-amino-2-chloro-3-R-CO-[N-(2'-cyano-biphenyl-4-ylmethyl)-amino]pyridine (VI) and this is treated with a strong acid, a 2-R-4-chloro-3-(2'-cyano-biphenyl-4-ylmethyl)-3H-imidazo[4,5-c]pyridine (VII) being formed as an intermediate.