153993-99-8Relevant articles and documents
Di-bromo-Based Small-Molecule Inhibitors of the PD-1/PD-L1 Immune Checkpoint
Konieczny, Magdalena,Musielak, Bogdan,Kocik, Justyna,Skalniak, Lukasz,Sala, Dominik,Czub, Miroslawa,Magiera-Mularz, Katarzyna,Rodriguez, Ismael,Myrcha, Maja,Stec, Malgorzata,Siedlar, Maciej,Holak, Tad A.,Plewka, Jacek
, p. 11271 - 11285 (2020/11/09)
Immune checkpoint blockade is one of the most promising strategies of cancer immunotherapy. However, unlike classical targeted therapies, it is currently solely based on expensive monoclonal antibodies, which often inflict immune-related adverse events. H
BENZOXAZINE DERIVATIVES AS GLYCINE TRANSPORT INHIBITORS
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Page/Page column 72-73, (2011/04/14)
The present invention relates to benzoxazinone derivatives, processes for their preparation, pharmaceutical compositions and medicaments containing them and to their use in treating disorders mediated by Gly T1, including neurological and neuropsychiatric disorders, in particular psychoses, dementia or attention deficit disorder.
NOVEL INDOLE DERIVATES AS FABP-4 INHIBITORS
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Page 34-35, (2010/02/07)
The present invention relates to novel compounds (I) wherein R0, R1, R2, R3, R4, R5, R6, R7, R8, A, B, n, X, and Y are as defined in the description and claims; and also to pharmaceutical compositions comprising the compounds, as well as to the use of the compounds in medicine and for the preparation of a medicament, which acts on the fatty acid binding protein FABP-4. The present invention relates to novel compounds (I) wherein R0, R1, R2, R3, R4, R5, R6, R7, R8, A, B, n, X, and Y are as defined in the description and claims; and also to pharmaceutical compositions comprising the compounds, as well as to the use of the compounds in medicine and for the preparation of a medicament, which acts on the fatty acid binding protein FABP-4.