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153993-99-8

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153993-99-8 Usage

General Description

2-Pyridinecarbonitrile, 4-(bromomethyl)-(9CI) is a chemical compound with the molecular formula C7H5BrN2. It is a brominated derivative of pyridinecarbonitrile, which is commonly used in the pharmaceutical and agrochemical industries as a building block for the synthesis of various compounds. The presence of the bromomethyl group in this compound makes it useful for the introduction of the bromine moiety into complex organic molecules. It is also used as a reagent in organic synthesis to introduce the cyano group into organic molecules. 2-Pyridinecarbonitrile,4-(bromomethyl)-(9CI) may have potential applications in the development of new drugs and agrochemicals due to its unique chemical properties. However, it should be handled with care and in accordance with proper safety protocols due to its potentially hazardous nature.

Check Digit Verification of cas no

The CAS Registry Mumber 153993-99-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,3,9,9 and 3 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 153993-99:
(8*1)+(7*5)+(6*3)+(5*9)+(4*9)+(3*3)+(2*9)+(1*9)=178
178 % 10 = 8
So 153993-99-8 is a valid CAS Registry Number.

153993-99-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-(bromomethyl)pyridine-2-carbonitrile

1.2 Other means of identification

Product number -
Other names 4-bromomethyl-2-pyridinecarbonitrile

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:153993-99-8 SDS

153993-99-8Relevant articles and documents

Di-bromo-Based Small-Molecule Inhibitors of the PD-1/PD-L1 Immune Checkpoint

Konieczny, Magdalena,Musielak, Bogdan,Kocik, Justyna,Skalniak, Lukasz,Sala, Dominik,Czub, Miroslawa,Magiera-Mularz, Katarzyna,Rodriguez, Ismael,Myrcha, Maja,Stec, Malgorzata,Siedlar, Maciej,Holak, Tad A.,Plewka, Jacek

, p. 11271 - 11285 (2020/11/09)

Immune checkpoint blockade is one of the most promising strategies of cancer immunotherapy. However, unlike classical targeted therapies, it is currently solely based on expensive monoclonal antibodies, which often inflict immune-related adverse events. H

BENZOXAZINE DERIVATIVES AS GLYCINE TRANSPORT INHIBITORS

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Page/Page column 72-73, (2011/04/14)

The present invention relates to benzoxazinone derivatives, processes for their preparation, pharmaceutical compositions and medicaments containing them and to their use in treating disorders mediated by Gly T1, including neurological and neuropsychiatric disorders, in particular psychoses, dementia or attention deficit disorder.

NOVEL INDOLE DERIVATES AS FABP-4 INHIBITORS

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Page 34-35, (2010/02/07)

The present invention relates to novel compounds (I) wherein R0, R1, R2, R3, R4, R5, R6, R7, R8, A, B, n, X, and Y are as defined in the description and claims; and also to pharmaceutical compositions comprising the compounds, as well as to the use of the compounds in medicine and for the preparation of a medicament, which acts on the fatty acid binding protein FABP-4. The present invention relates to novel compounds (I) wherein R0, R1, R2, R3, R4, R5, R6, R7, R8, A, B, n, X, and Y are as defined in the description and claims; and also to pharmaceutical compositions comprising the compounds, as well as to the use of the compounds in medicine and for the preparation of a medicament, which acts on the fatty acid binding protein FABP-4.

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