154019-99-5Relevant articles and documents
DEVELOPMENT OF NEW DNA-BINDING AND CLEAVING MOLECULES: DESIGN, SYNTHESIS AND ACTIVITY OF A BISDIAZONIUM SALT
Arya, Dev P.,Warner, Philip M.,Jebaratnam, David J.
, p. 7823 - 7826 (1993)
The bisdiazonium compound 1 has been shown to cleave DNA at concentrations as low as 0.1 μM.Evidence is presented to indicate that 1 is binding to the minor groove of DNA, and that binding may be responsible for its effectiveness as a DNA cleaving reagent