154106-04-4

Basic information

• Product Name: 2-(4-methoxybenzoyl)-N-methylhydrazine-1-carbothioamide
• Synonyms: 2-(4-methoxybenzoyl)-N-methylhydrazine-1-carbothioamide
• CAS NO: 154106-04-4
• Molecular Weight: 239.298
• Mol File: 154106-04-4.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 2-(4-methoxybenzoyl)-N-methylhydrazine-1-carbothioamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-methoxybenzoyl)-N-methylhydrazine-1-carbothioamide(154106-04-4)
• EPA Substance Registry System: 2-(4-methoxybenzoyl)-N-methylhydrazine-1-carbothioamide(154106-04-4)

Safety Data

• Hazardous Substances Data: 154106-04-4(Hazardous Substances Data)

Upstream product

• 100-07-2 4-methoxy-benzoyl chloride 
• 6610-29-3 4-methylthiosemicarbazide 
• 593-75-9 methyl isocyanate 
• 3290-99-1 4-methoxybenzoic acid hydrazide 
• 556-61-6 methyl thioisocyanate 

Downstream Products

• 57295-61-1 3-(4-methoxyphenyl)-4-methyl-5-(methylthio)-4H-1,2,4-triazole 
• 746583-68-6 (6R,7R)-7-{2-(2-Amino-thiazol-4-yl)-2-[(Z)-methoxyimino]-acetylamino}-3-[5-(4-methoxy-phenyl)-4-methyl-4H-[1,2,4]triazol-3-ylsulfanylmethyl]-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid 
• 177713-75-6 (6R,7R)-7-Amino-3-[5-(4-methoxy-phenyl)-4-methyl-4H-[1,2,4]triazol-3-ylsulfanylmethyl]-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid 
• 57295-83-7 5-(4-methoxyphenyl)-4-methyl-2,4-dihydro-3H-1,2,4-triazole-3-thione 

Relevant articles and documents

Catalytic Production of Isothiocyanates via a Mo(II)/Mo(IV) Cycle for the "soft" Sulfur Oxidation of Isonitriles

In the presence of excess amounts of elemental sulfur, the dimolybdenum dinitrogen complex {CpMo[N(iPr)C(Ph)N(iPr)]}2(μ-N2) (4; Cp? = η5-C5Me5) serves as a precatalyst for the production of isothiocyanates from isonitriles via highly efficient and atom-economical metal-mediated sulfur atom transfer (SAT) under mild conditions. Mechanistic and structural studies support a catalytic cycle for SAT involving initial formation of a Mo(II) bis(isonitrile) complex that then undergoes sulfination to generate a formal "side-bound" Mo(IV) κ 2-(C,S)-isothiocyanate as the key intermediate. This metal-catalyzed SAT process has further been employed for the "on-demand" production of isothiocyanates that are trapped in situ by benzhydrazides to provide thiosemicarbazides, which are useful precursors to biologically active thiadiazoles.

Design, synthesis and antibacterial evaluation of 1-[(1R,2S)-2-Fluorocyclopropyl] Ciprofloxacin-(4-Methyl-3-Aryl)-1,2,4-Triazole-5(4H)-Thione Hybrids

Fourteen novel 1-[(1R,2S)-2-Fluorocyclopropyl]ciprofloxac in-(4-methyl-3-aryl)-1,2,4-triazole-5(4H)-thione hybrids 6a-n were designed, synthesized and assessed for their in vitro antibacterial activities against representative Gram-positive and Gram-negat

5-Aryl-3-(alkylthio)-4H-1,2,4-triazoles as selective antagonists of strychnine-induced convulsions and potential antispastic agents

Selected examples from three series of isomeric (alkylthio)-1,2,4- triazoles were prepared and examined for anticonvulsant activity versus strychnine-, maximal-electroshock-, pentylenetetrazole-, and 3- mercaptopropionic-acid-induced seizures in mice. A n