154188-75-7

Basic information

• Product Name: 1H-Isoindole-1,3(2H)-dione, 2-(5-phenyl-4-pentynyl)-
• CAS NO: 154188-75-7
• Molecular Formula: C19H15NO2
• Molecular Weight: 289.334
• Mol File: 154188-75-7.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: 1H-Isoindole-1,3(2H)-dione, 2-(5-phenyl-4-pentynyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Isoindole-1,3(2H)-dione, 2-(5-phenyl-4-pentynyl)-(154188-75-7)
• EPA Substance Registry System: 1H-Isoindole-1,3(2H)-dione, 2-(5-phenyl-4-pentynyl)-(154188-75-7)

Safety Data

• Hazardous Substances Data: 154188-75-7(Hazardous Substances Data)

Upstream product

• 108-86-1 bromobenzene 
• 6097-07-0 N-(pent-4-ynyl)phthalimide 
• 136918-14-4 phthalimide 
• 28077-72-7 1-bromo-4-pentyne 
• 591-50-4 iodobenzene 
• 4440-01-1 lithium phenylacetylide 
• 24595-58-2 5-phenylpent-4-yn-1-ol 
• 92994-35-9 2-(5-phenylpent-4-ynyloxy)tetrahydro-2H-pyran 
• 14267-92-6 1-chloro-4-pentyne 
• 57718-13-5 (5-bromo-pent-1-ynyl)-benzene 
• 24463-87-4 (5-chloropent-1-ynyl)benzene 
• 1074-82-4 potassium phtalimide 

Downstream Products

• 127808-49-5 5-phenylpent-4-yn-1-amine 

Relevant articles and documents

Cobalt-Catalyzed Regioselective Carboamidation of Alkynes with Imides Enabled by Cleavage of C-N and C-C Bonds

Through the oxidative addition of cobalt into the N-C(O) bond of phthalimide and the subsequent decarbonylation, we describe an efficient cobalt-catalyzed intermolecular decarbonylative carboamidation of alkynes. High regioselectivities have been achieved for unsymmetrical alkynes (including aryl-alkyl or aryl-aryl) to deliver polysubstituted isoquinolones. To facilitate step economy, a three-component decarbonylative carboamidation of alkynes with phthalic anhydrides and amines has been demonstrated using the current cobalt catalysis.

Facile one-pot synthesis of 2,3-dihydro-1H-indolizinium derivatives by rhodium(iii)-catalyzed intramolecular oxidative annulation via C-H activation: application to ficuseptine synthesis

Various substituted indolizidinium, quinolizinium and pyrido[1,2-a]azepinium salts synthesized from benzaldehydes (or α,β-unsaturated aldehydes) and alkyne-amines catalyzed by rhodium complexes via C-H activation are demonstrated. The reaction was carried

Copper-catalyzed highly selective semihydrogenation of non-polar carbon-carbon multiple bonds using a silane and an alcohol

A copper catalyst bearing a suitable Xantphos derivative or NHC ligand was found to be highly efficient for the selective semihydrogenation of non-polar unsaturated compounds using a mixture of a silane and an alcohol as reducing agent. The catalytic system was useful for the selective semihydrogenation of internal alkynes to (Z)-alkenes with suppression of overreduction to the corresponding alkanes. Furthermore, semihydrogenations of terminal alkyne, 1,2-diene, 1,3-diene, 1,3-enyne and 1,3-diyne systems were also achieved selectively. Copyright