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1542224-29-2

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1542224-29-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1542224-29-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,5,4,2,2,2 and 4 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1542224-29:
(9*1)+(8*5)+(7*4)+(6*2)+(5*2)+(4*2)+(3*4)+(2*2)+(1*9)=132
132 % 10 = 2
So 1542224-29-2 is a valid CAS Registry Number.

1542224-29-2Relevant articles and documents

Discovery and optimization of tetramethylpiperidinyl benzamides as inhibitors of EZH2

Nasveschuk, Christopher G.,Gagnon, Alexandre,Garapaty-Rao, Shivani,Balasubramanian, Srividya,Campbell, Robert,Lee, Christina,Zhao, Feng,Bergeron, Louise,Cummings, Richard,Trojer, Patrick,Audia, James E.,Albrecht, Brian K.,Harmange, Jean-Christophe P.

, p. 378 - 383 (2014/05/06)

The identification and development of a novel series of small molecule Enhancer of Zeste Homologue 2 (EZH2) inhibitors is described. A concise and modular synthesis enabled the rapid development of structure-activity relationships, which led to the identification of 44 as a potent, SAM-competitive inhibitor of EZH2 that dose-dependently decreased global H3K27me3 in KARPAS-422 lymphoma cells.

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