154321-02-5

Basic information

• Product Name: ethyl <2-(3-bromophenyl)-1(S)-methyl-2-oxoethyl>carbamate
• CAS NO: 154321-02-5
• Molecular Weight: 300.152
• Mol File: 154321-02-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: ethyl <2-(3-bromophenyl)-1(S)-methyl-2-oxoethyl>carbamate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl <2-(3-bromophenyl)-1(S)-methyl-2-oxoethyl>carbamate(154321-02-5)
• EPA Substance Registry System: ethyl <2-(3-bromophenyl)-1(S)-methyl-2-oxoethyl>carbamate(154321-02-5)

Safety Data

• Hazardous Substances Data: 154321-02-5(Hazardous Substances Data)

Upstream product

• 16639-86-4 N-ethoxycarbonyl-L-alanine 
• 108-36-1 1,3-dibromobenzene 

Downstream Products

• 154321-07-0 ethyl <5-amino-3-(3-bromophenyl)-1,2-dihydro-2(S)-methylpyrido<3,4-b>pyrazin-7-yl>carbamate 
• 154321-06-9 ethyl <6-amino-4-<<2-(3-bromophenyl)-1-methyl-2-oxoethyl>amino>-5-nitro-2-pyridinyl>carbamate 

Relevant articles and documents

Synthesis of [3H]CI-980, ethyl[5-amino-1,2-dihydro-2(S)-methyl-3(3-[3H]phenyl)pyrido[3,4-b]pyr azin-7-yl]carbamate isethionate salt, a tubulin-binding, antimitotic, broad-spectrum antitumor agent

[3H]CI-980 (10b) was synthesized in an eight-step sequence with an overall yield of 2.4%. Reaction of m-bromophenyl lithium (2) with N-ethoxycarbonyl-L-alanine gave the chiral ketone 3. Reduction of 3 with sodium borohydride followed by alkalin