15441-65-3

Basic information

• Product Name: 3-Pentyn-2-one, 5-hydroxy-
• Synonyms: 5-hydroxy-3-pentyn-2-one;Pentin-(2)-ol-(1)-on-(4);3-Pentyn-2-one,5-hydroxy;5-Hydroxy-pent-3-in-2-on;5-hydroxy-pent-3-yn-2-one
• CAS NO: 15441-65-3
• Molecular Formula: C5H6O2
• Molecular Weight: 98.1014
• Mol File: 15441-65-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-Pentyn-2-one, 5-hydroxy-(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Pentyn-2-one, 5-hydroxy-(15441-65-3)
• EPA Substance Registry System: 3-Pentyn-2-one, 5-hydroxy-(15441-65-3)

Safety Data

• Hazardous Substances Data: 15441-65-3(Hazardous Substances Data)

Upstream product

• 94145-20-7 ammonium salt of 2,6-dihydroxy-3-(β-hydroxyethyl)-4-methyl-5-cyanopyridine 
• 100-46-9 benzylamine 

Relevant articles and documents

DERIVATIVES OF AZYINDOLES. 65. SYNTHESIS OF 1-BENZYL-4-METHYL-5-CYANO-6-HYDROXY-7-AZAINDOLINE

Treatment of the ammonium (I) or benzylammonium salt of 2,6-dihydroxy-3-(β-hydroxyethyl)-4-methyl-5-cyanopyridine (II) with a mixture of benzylamine and phosphorus pentoxide yielded 2-benzylamino-3-(β-hydroxyethyl)-4-methyl-5-cyano -6-hydroxypyridine (III), which, when heated with phosphorus oxychloride, is converted to 1-benzyl-4-methyl-5-cyano-6-hydroxy-7-azaindoline (IV).The products of thermal fragmentation of II with benzylamine were studied by the method of chromato-mass spectrometry.In addition to compound III, N,N'-dibenzylurea (V) and the dibenzylamide of malonic acid (VI) were preparatively isolated from the reaction products .The cyclization of I and II to 4-methyl-6-hydroxy-2,3-dihydro-7-azabenzofuran (VII) and 4-methyl-5-cyano-6-hydroxy-2,3-dihydro-7-azabenzofuran (VIII) was carried out.Heating VIII with benzylamine at 200-210 grad C led to compound III.