15441-95-9Relevant articles and documents
Synthesis of 2,4-diaminoquinazoline derivatives
Zielinski, Wojciech,Kudelko, Agnieszka,Holt, Elizabeth M.
, p. 319 - 328 (2007/10/03)
A series of 6- and 7-substituted derivatives of 2-(N,N-diethylamino)-4-(N,N-dimethylamino)quinazoline have been synthesized. The synthesis consists in converting N-phenyl-N',N'-diethylurea into chloroamidines which are treated with N,N-dimethylcyanamide t
Process for the preparation of trisubstituted ureas
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, (2008/06/13)
The present invention provides a process for preparing a trisubstituted urea of the general formula: in which R is a substituted or unsubstituted mono-, di- or polyvalent aromatic radical, R' is a substituted or unsubstituted monovalent aliphatic or aromatic radical and R is a substituted or unsubstituted monovalent aliphatic radical or R' and R together represent a substituted or unsubstituted divalent radical in which at least one of the two carbon atoms adjoining the nitrogen atom of the urea is aliphatic, and n is an integer, wherein an aromatic nitrocompound of the general formula:--R(NO2)n or an aromatic nitrosocompound of the general formula:--R(NO)n is allowed to react with a secondary ammonium N,N-disubstituted thiolcarbamate of the general formula: or with a mixture of a secondary amine of the general formula:--R'R NH and carbon monoxide and sulphur, carbon monoxide and hydrogen sulphide, or carbonyl sulphide, or with a mixture of a secondary ammonium sulphide or hydrosulphide of the general formula: or and carbon monoxide.