15446-14-7 Usage
Description
1-chloro-4-(prop-2-en-1-ylsulfanyl)benzene, also known as thiophenol, is a chemical compound that consists of a benzene ring with a chlorine atom in the 1-position and a thiol group attached to the 4-position. The thiol group, also known as a sulfhydryl group, contains a sulfur atom bonded to a hydrogen atom and an alkene group, also called the prop-2-en-1-yl group. Thiophenol is a colorless to light yellow liquid with a strong, unpleasant odor similar to that of rotten garlic or skunk spray.
Uses
Used in Organic Synthesis:
1-chloro-4-(prop-2-en-1-ylsulfanyl)benzene is used as a reagent in organic synthesis for its ability to participate in various chemical reactions, such as nucleophilic substitution and electrophilic aromatic substitution. This makes it a versatile building block for the production of dyes, pharmaceuticals, and other organic compounds.
Used in Solvent Applications:
As a solvent, 1-chloro-4-(prop-2-en-1-ylsulfanyl)benzene is used to dissolve a wide range of substances, facilitating various chemical processes and reactions in the laboratory and industrial settings.
Used in Pharmaceutical Production:
1-chloro-4-(prop-2-en-1-ylsulfanyl)benzene is used as an intermediate in the synthesis of pharmaceuticals, contributing to the development of new drugs and medicines.
Used in Dye Production:
In the dye industry, 1-chloro-4-(prop-2-en-1-ylsulfanyl)benzene is used as a starting material or intermediate in the production of various dyes, providing color and functionality to textiles, plastics, and other materials.
Check Digit Verification of cas no
The CAS Registry Mumber 15446-14-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,5,4,4 and 6 respectively; the second part has 2 digits, 1 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 15446-14:
(7*1)+(6*5)+(5*4)+(4*4)+(3*6)+(2*1)+(1*4)=97
97 % 10 = 7
So 15446-14-7 is a valid CAS Registry Number.
15446-14-7Relevant articles and documents
Synthesis of sulfides under solvent- and catalyst-free conditions
Movassagh, Barahman,Soleiman-Beigi, Mohammad
, p. 409 - 411 (2009)
A simple, highly efficient, and green protocol has been developed for preparation of sulfides from alkyl or aryl thiols and benzyl-, allyl-, t-butyl, and adamantyl halides under solvent- and catalyst-free conditions.
Synthesis of sulfimides and N-Allyl-N-(thio)amides by Ru(II)catalyzed nitrene transfer reactions of N-acyloxyamides
Zhang, Xinyu,Lin, Bo,Chen, Jianhui,Chen, Jiajia,Luo, Yanshu,Xia, Yuanzhi
supporting information, p. 819 - 825 (2021/02/01)
The N-acyloxyamides were employed as effective N-acyl nitrene precursors in reactions with thioethers under the catalysis of a commercially available Ru(II) complex, from which a variety of sulfimides were synthesized efficiently and mildly. If an allyl group is contained in the thioether precursor, the [2,3]-sigmatropic rearrangement of the sulfimide occurs simultaneously and the N-allyl-N-(thio)amides were obtained as the final products. Preliminary mechanistic studies indicated that the Ru-nitrenoid species should be a key intermediate in the transformation.
One-pot Synthesis of Allyl Sulfides from Sulfinate Esters and Allylsilanes through Reduction of Alkoxysulfonium Intermediates
Hosoya, Takamitsu,Kobayashi, Akihiro,Matsuzawa, Tsubasa,Yoshida, Suguru
supporting information, p. 813 - 816 (2020/07/23)
An efficient method to synthesize allyl sulfides from sulfinate esters and allylsilanes is described. Based on the reactivity of isolated allyl(methoxy)phenyl sulfonium triflate, we have developed a simple one-pot method for the allyl sulfide synthesis by S-allylation of sulfinate esters and subsequent reduction with sodium borohydride. A number of allyl sulfides were prepared by this method leaving various functional groups unreacted.
