1547162-41-3 Usage
Description
5-Hydroxypomalidomide, also known as 4-amino-2-(2,6-dioxo-3-piperidinyl)-5-hydroxy-1H-isoindole-1,3(2H)-dione, is an impurity of Pomalidomide (P688200). Pomalidomide is a thalidomide derivative with potent inhibitory effects on TNF-α production. It is characterized by its anti-inflammatory and antitumor properties.
Uses
Used in Pharmaceutical Industry:
5-Hydroxypomalidomide is used as an impurity in the production of Pomalidomide, which is an anti-inflammatory and antitumor agent. The application reason is that Pomalidomide is utilized in the treatment of multiple myeloma, a type of blood cancer. By inhibiting TNF-α production, Pomalidomide helps in reducing inflammation and tumor growth, making it a valuable compound in the pharmaceutical industry for cancer treatment.
Additionally, if there are other applications in different industries, they can be listed as follows:
Used in Research and Development:
5-Hydroxypomalidomide can be used as a research compound for studying the structure-activity relationship of Pomalidomide and its analogs. This application is important for understanding the molecular mechanisms of action and potentially developing new therapeutic agents with improved efficacy and reduced side effects.
Used in Quality Control:
5-Hydroxypomalidomide may also be used in the quality control process of Pomalidomide manufacturing. By monitoring the levels of this impurity, manufacturers can ensure the purity and safety of the final drug product, which is crucial for patient safety and compliance with regulatory standards.
Check Digit Verification of cas no
The CAS Registry Mumber 1547162-41-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,5,4,7,1,6 and 2 respectively; the second part has 2 digits, 4 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1547162-41:
(9*1)+(8*5)+(7*4)+(6*7)+(5*1)+(4*6)+(3*2)+(2*4)+(1*1)=163
163 % 10 = 3
So 1547162-41-3 is a valid CAS Registry Number.
1547162-41-3Relevant articles and documents
PROCESSES FOR PREPARING ISOINDOLINE-1,3-DIONE COMPOUNDS
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, (2014/02/16)
Provided herein are processes for preparing an isoindoline- 1.3-dione compound, or an enantiomer or a mixture of enantiomers thereof; or a pharmaceutically acceptable salt, solvate, hydrate, or polymorph thereof.
