1548331-45-8Relevant articles and documents
Application of substituted mono carbonyl curcumin compound containing allyl in preparing antitumor drug
-
Paragraph 0093; 0116, (2017/05/02)
The invention discloses application of a substituted mono carbonyl curcumin compound containing allyl in preparing antitumor drug. The mono carbonyl curcumin compound has a structure shown in a formula (I) or a pharmaceutically acceptable salt thereof, wherein A represents C, S, or O -NR1, R1 is independently selected from one or more of H, C1-C5 alkyl, phenyl benzene and benzyl group, n is 0 or 1, R is independently selected from one or more of H, hydroxyl, C1-C4, alkoxyl, pyrrolidine, morpholinyl and methyl N-piperazine. Test results show that the mono carbonyl curcumin compound has good stability and antitumor activity, and can be used as a potential antitumor drug.