154902-50-8Relevant articles and documents
Asymmetric syntheses of (S)-Fenfluramine using Sharpless Epoxidation Methods
Goument, Bertrand,Duhamel, Lucette,Mauge, Robert
, p. 171 - 188 (2007/10/02)
We describe one synthesis of (S)-fenfluramine and several syntheses of its precursors (R)- and (S)-1-(meta-trifluoromethylphenyl)propan-2-ols.They were obtained from the asymmetric epoxidation of the primary allylic alcohol 5 and from the kinetic resolution with asymmetric epoxidation of teh secondary allylic alcohol 6.