154971-65-0

Basic information

• Product Name: 2',3',5'-tri-O-benzoyladenosine 6-N-(O,O-bis(2-cyanoethyl)phosphoramidate)
• Synonyms: 2',3',5'-tri-O-benzoyladenosine 6-N-(O,O-bis(2-cyanoethyl)phosphoramidate)
• CAS NO: 154971-65-0
• Molecular Weight: 765.676
• Mol File: 154971-65-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2',3',5'-tri-O-benzoyladenosine 6-N-(O,O-bis(2-cyanoethyl)phosphoramidate)(CAS DataBase Reference)
• NIST Chemistry Reference: 2',3',5'-tri-O-benzoyladenosine 6-N-(O,O-bis(2-cyanoethyl)phosphoramidate)(154971-65-0)
• EPA Substance Registry System: 2',3',5'-tri-O-benzoyladenosine 6-N-(O,O-bis(2-cyanoethyl)phosphoramidate)(154971-65-0)

Safety Data

• Hazardous Substances Data: 154971-65-0(Hazardous Substances Data)

Upstream product

• 58-61-7 adenosine 
• 93-97-0 benzoic acid anhydride 
• 51549-15-6 2',3',5'-tri-O-benzoyladenosine 
• 102690-88-0 bis(2-cyanoethyl) diisopropylamidophosphite 

Relevant articles and documents

New strategies for the chemical synthesis of biologically important nucleic acid derivatives

This paper describes general methods for the synthesis of N- phosphorylated ribonucleosides and oligonucleotides containing a 2'-O- phosphorylated or 2'-O-thiophosphorylated ribonucleoside. The NMR-based conformational analysis and computational molecular dynamics simulation of the 2'-O-phosphorylated ribonucleoside residue in such modified oligonucleotides suggested that the ribose residue existed preferentially in a C2'-endo conformation. It was also found that simple heating of 2'-O- phosphorylated oligonucleotides resulted in rapid dethiophosphorylation.