155186-38-2Relevant articles and documents
Studies of HIV-1 protease inhibitors. II. Incorporation of four types of hydroxyethylene dipeptide isosteres at the scissile site of substrate sequences
Sakurai,Higashida,Sugano,Nishi,Saito,Ohata,Handa,Komai,Yagi,Nishigaki,Yabe
, p. 1378 - 1386 (2007/10/02)
Human immunodeficiency virus type 1 (HIV-1) protease inhibitors containing four types of hydroxyethylene dipeptide isosteres were designed and synthesized. These inhibitors consist of eight stereoisomers of phenylalanylproline (Phe-Ψ[H.E.]-Pro), four ster