155239-47-7Relevant articles and documents
The synthesis of glucuronides derived from the antidepressant drugs mianserin and Org 3770
Van Boeckel,Delbressine,Kaspersen
, p. 259 - 265 (2007/10/02)
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155239-47-7
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Basic information
- Product Name: 8-Hydroxy Mirtazapine
- Synonyms: 8-Hydroxymirtazapine b-D-glucuronide;8-Hydroxy Mirtazapine β-D-Glucuronide 90%;8-Hydroxy Mirtazapine β-D-Glucuronide
- CAS NO:155239-47-7
- Molecular Formula: C23H27N3O7
- Molecular Weight: 457.47638
- EINECS: N/A
- Product Categories: Glucuronides;Heterocycles;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals;Glucuronides, Heterocycles, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
- Mol File: 155239-47-7.mol
- Article Data: 1
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Chemical Properties
- Melting Point: 210-214°C (dec.)
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: Hygroscopic, -20?C Freezer, Under Inert Atmosphere
- Solubility: Methanol (Slightly), Water (Slightly)
- CAS DataBase Reference: 8-Hydroxy Mirtazapine(CAS DataBase Reference)
- NIST Chemistry Reference: 8-Hydroxy Mirtazapine(155239-47-7)
- EPA Substance Registry System: 8-Hydroxy Mirtazapine(155239-47-7)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 155239-47-7(Hazardous Substances Data)
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155239-47-7 Usage
Description
8-Hydroxy Mirtazapine, also known as M365000, is a metabolite of Mirtazapine, an antidepressant medication. It is characterized by its pink solid appearance and contains some of the alpha anomer. As a metabolite, 8-Hydroxy Mirtazapine may possess similar or distinct pharmacological properties compared to its parent compound, Mirtazapine.Uses
Used in Pharmaceutical Industry:8-Hydroxy Mirtazapine is used as a research compound for studying its potential therapeutic applications and understanding its pharmacological properties. As a metabolite of Mirtazapine, it may have implications in the treatment of various psychiatric disorders, including depression and anxiety.
Used in Chemical Research:
8-Hydroxy Mirtazapine is used as a chemical intermediate in the synthesis of other related compounds. Its unique chemical structure and properties make it a valuable starting material for the development of new drugs or drug candidates with potential applications in various therapeutic areas.
Used in Analytical Chemistry:
8-Hydroxy Mirtazapine can be used as a reference compound in analytical chemistry for the development and validation of analytical methods, such as high-performance liquid chromatography (HPLC) or mass spectrometry (MS), for the detection and quantification of Mirtazapine and its metabolites in biological samples.
Used in Drug Metabolism Studies:
8-Hydroxy Mirtazapine is used as a model compound in drug metabolism studies to investigate the metabolic pathways and enzyme systems involved in the biotransformation of Mirtazapine. This information can be valuable for understanding the pharmacokinetics and pharmacodynamics of Mirtazapine and its metabolites, as well as for the design of new drugs with improved safety and efficacy profiles.
Check Digit Verification of cas no
The CAS Registry Mumber 155239-47-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,5,2,3 and 9 respectively; the second part has 2 digits, 4 and 7 respectively.Calculate Digit Verification of CAS Registry Number 155239-47:
(8*1)+(7*5)+(6*5)+(5*2)+(4*3)+(3*9)+(2*4)+(1*7)=137
137 % 10 = 7
So 155239-47-7 is a valid CAS Registry Number.
155239-47-7Upstream product
155239-47-7Downstream Products
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8-Hydroxy Mirtazapine
