155271-11-7

Basic information

• Product Name: 8-[(E)-2-(2,4-dimethoxy-3-methylphenyl)ethenyl]-1,3-diethyl-7-methyl-3,7-dihydro-1H-purine-2,6-dione
• Synonyms: 1H-purine-2,6-dione, 8-[(E)-2-(2,4-dimethoxy-3-methylphenyl)ethenyl]-1,3-diethyl-3,7-dihydro-7-methyl-
• CAS NO: 155271-11-7
• Molecular Formula: C₂₁H₂₆N₄O₄
• Molecular Weight: 398.4555
• Mol File: 155271-11-7.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 611.3°C at 760 mmHg
• Flash Point: 323.5°C
• Density: 1.22g/cm³
• Vapor Pressure: 6.96E-15mmHg at 25°C
• Refractive Index: 1.593
• CAS DataBase Reference: 8-[(E)-2-(2,4-dimethoxy-3-methylphenyl)ethenyl]-1,3-diethyl-7-methyl-3,7-dihydro-1H-purine-2,6-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 8-[(E)-2-(2,4-dimethoxy-3-methylphenyl)ethenyl]-1,3-diethyl-7-methyl-3,7-dihydro-1H-purine-2,6-dione(155271-11-7)
• EPA Substance Registry System: 8-[(E)-2-(2,4-dimethoxy-3-methylphenyl)ethenyl]-1,3-diethyl-7-methyl-3,7-dihydro-1H-purine-2,6-dione(155271-11-7)

Safety Data

• Hazardous Substances Data: 155271-11-7(Hazardous Substances Data)

Upstream product

• 155271-10-6 (E)-8-(2, 4-Dimethoxy-3-methylstyryl)-1,3-diethylxanthine 
• 74-88-4 methyl iodide 
• 52998-22-8 5,6-diamino-1,3-diethyluracil 

Relevant articles and documents

Adenosine A(2A) antagonists with potent anti-cataleptic activity

Structure-activity relationships of 8-styrylxanthines for in vivo adenosine A(2A) antagonism were explored. Diethyl substitution both at the 1- and S-position was found to dramatically potentiate the anti-cataleptic activity.

Antidepressants

The present invention relates to an antidepressant containing as an active ingredient a xanthine derivative or a pharmaceutically acceptable salt thereof, the xanthine derivative being represented by Formula (I) : STR1 in which R1, R2, and R3 represent independently hydrogen, lower alkyl, lower alkenyl; R4 represents cycloalkyl, --(CH2)n --R5 (in which R5 represents substituted or unsubstituted aryl or a substituted or unsubstituted heterocyclic group; and n is an integer of 0 to 4), or STR2 (in which Y1 and Y2 represent independently hydrogen, halogen or lower alkyl; and Z represents substituted or unsubstituted aryl, STR3 (in which R6 represents hydrogen, hydroxy, lower alkyl, lower alkoxy, halogen, nitro, or amino; and m represents an integer of 1 to 3), or a substituted or unsubstituted heterocyclic group); and X1 and X2 represent independently O or S.