15544-49-7

Basic information

• Product Name: N-(N⁴-p-toluenesulfonyl)-4-aminobutylphthalimide
• Synonyms: N-(N⁴-p-toluenesulfonyl)-4-aminobutylphthalimide
• CAS NO: 15544-49-7
• Molecular Weight: 372.445
• Mol File: 15544-49-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: N-(N⁴-p-toluenesulfonyl)-4-aminobutylphthalimide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(N⁴-p-toluenesulfonyl)-4-aminobutylphthalimide(15544-49-7)
• EPA Substance Registry System: N-(N⁴-p-toluenesulfonyl)-4-aminobutylphthalimide(15544-49-7)

Safety Data

• Hazardous Substances Data: 15544-49-7(Hazardous Substances Data)

Upstream product

• 86101-33-9 N-<(4-(N-nitroso-p-toluenesulfonamido)-1-butyl)>phthalimide 
• 22509-74-6 N-ethoxycarbonylphthalimide 
• 78521-64-9 N-(4-aminobutyl)-4-methyl benzenesulfonamide 
• 136918-14-4 phthalimide 
• 100649-38-5 N-(4-bromobutyl)-4-methylbenzenesulfonamide 
• 3184-61-0 4-phthalimidobutyronitrile 
• 5460-29-7 2-(3-bromopropyl)isoindole-1,3-dione 
• 98-59-9 p-toluenesulfonyl chloride 
• 35517-18-1 N-(4-amino-1-butyl)phthalimide hydrochloride 

Downstream Products

• 86101-33-9 N-<(4-(N-nitroso-p-toluenesulfonamido)-1-butyl)>phthalimide 
• 86088-63-3 N-<4-butyl>phthalimide 
• 5457-30-7 4-phthalimido-1-iodobutane 
• 86088-65-5 N-(4-hydroxy-1-butyl)phthalimide tosylate 
• 202065-58-5 {4-[[4-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-butyl]-(toluene-4-sulfonyl)-amino]-butyl}-phosphinic acid ethyl ester 
• 202065-56-3 {4-[[4-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-butyl]-(toluene-4-sulfonyl)-amino]-butyl}-phosphinic acid 
• 277760-26-6 N¹-etyl-N¹,N⁴-di(p-toluenesulfonyl)-N⁸-formyl-1,8-diamino-4-azaoctane 
• 124040-16-0 N¹,N⁴-di(p-toluenesulfonyl)-N⁸-formyl-1,8-diamino-4-azaoctane 
• 202065-53-0 N-[4-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-butyl]-N-(4-iodo-butyl)-4-methyl-benzenesulfonamide 
• 15440-91-2 N-(4-phthalimido-butyl)-N-[3-(2-oxo-oxazolidin-3-yl)-propyl]-toluene-4-sulfonamide 

Relevant articles and documents

RNA polymerase transcription promoters and nucleic acid sequencing method

An RNA polymerase transcription accelerator comprising a compound represented by the following Formula (I) or salts thereof. A method of sequencing DNA in which nucleic acid transcripts are obtained using an RNA polymerase and a DNA fragment as a template, the resulted nucleic acid transcripts are separated, the nucleic acid sequence is determined from the separated fractions wherein the nucleic acid transcription reaction is carried out in the presence of a compound selected from a group of compounds represented by the above formula (I). The polyamine compounds above have outstanding accelerating activity on transcription activity of RNA polymerase. Therefore, use of the polyamine compounds in a DNA sequencing method using RNA polymerase can make a length of DNA sequence that can be determined in one sequencing longer.

Biosynthesis of streptothricin F. 5. Formation of β-lysine by Streptomyces L-1689-23

The formation of the β-lysine moiety of streptothricin F has been studied by feeding to Streptomyces L-1689-23 α-[3-13C,15N]-, α-[(3RS)-2H2]-, α-[(3R)-2H]-, and α[(3S)-2H]lysine and β-[(2S)-2H]lysine. From the analysis of either the 13C NMR or 2H NMR spectrum of the derived antibiotics, it has been determined that the α-nitrogen migrates to C-3 with inversion of configuration by an intramolecular process, and the 3-pro-R hydrogen migrates to C-2 with inversion of configuration by a process that is substantially or completely intermolecular. The very high degree of incorporation of labeled β-lysine indicates it is probably an intermediate in the biosynthesis of streptothricin F. The formation of the beta -lysine moiety of streptothricin F has been studied by feeding to Streptomyces L-1689-23 alpha - left bracket 3-**1**3C, **1**5N right bracket -, alpha - left bracket (3RS)-**2H//2 right bracket -, alpha - left bracket (3R)-**2H right bracket -, and alpha - left bracket (3S)-**2H right bracket lysine and beta - left bracket (2S)-**2H right bracket lysine. From the analysis of either the **1**3C NMR or **2H NMR spectrum of the derived antibotics, it has been determined that the alpha -nitrogen migrates to C-3 with inversion of configuration by an intramolecular process, and the 3-pro-R hydrogen migrates to C-2 with inversion of configuration by a process that is substantially or completely intermolecular. The very high degree of incorporation of labeled beta -lysine indicates it is probably an intermediate in the biosynthesis of streptothricin F.