1558-17-4 Usage
Description
4,6-Dimethylpyrimidine is an organic compound characterized by the presence of two methyl groups at the 4th and 6th positions of the pyrimidine ring. It is a clear yellowish liquid after melting and is known for its versatile applications across different industries.
Uses
1. Pharmaceutical Industry:
4,6-Dimethylpyrimidine is used as a pharmaceutical intermediate for the production of various drugs. Specifically, it is utilized in the synthesis of (6-methyl-pyrimidin-4-yl)-pyruvic acid ethyl ester, which is a key component in the development of certain pharmaceuticals.
2. Agrochemical Industry:
In the agrochemical sector, 4,6-dimethylpyrimidine serves as an essential intermediate compound in the development of various agrochemical products. Its unique chemical properties make it a valuable component in the formulation of pesticides, herbicides, and other agricultural chemicals.
3. Dyestuff Industry:
4,6-Dimethylpyrimidine is also employed in the dyestuff industry, where it is used as a crucial intermediate in the production of different types of dyes. Its chemical structure contributes to the development of dyes with specific color properties and applications in various industries, such as textiles, plastics, and printing.
Synthesis Reference(s)
Journal of Heterocyclic Chemistry, 19, p. 373, 1982 DOI: 10.1002/jhet.5570190231
Check Digit Verification of cas no
The CAS Registry Mumber 1558-17-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,5,5 and 8 respectively; the second part has 2 digits, 1 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1558-17:
(6*1)+(5*5)+(4*5)+(3*8)+(2*1)+(1*7)=84
84 % 10 = 4
So 1558-17-4 is a valid CAS Registry Number.
InChI:InChI=1/C6H8N2/c1-5-3-6(2)8-4-7-5/h3-4H,1-2H3
1558-17-4Relevant articles and documents
Vapor phase phototransposition chemistry of dimethylpyrazines and dimethylpyrimidines
Pavlik, James W.,Vongakorn, Tharinee,Kebede, Naod
, p. 216 - 228 (2017/11/17)
Based on their phototransposition chemistry, the three dimethylpyrazines and four dimethylpyrimidines can be arranged into two groups. 2,5-Dimethylpyrazine, 2,5-dimethylpyrimidine, and 4,6-dimethylpyrimidine constitute a photochemical triad. Irradiation of any one member of the triad in the vapor phase results in the formation of the other two members. The other four isomers, 2,6-dimethylpyrazine, 2,3-dimethylpyrazine, 2,4- dimethylpyrimidine, and 4,5-dimethylpyrimidine constitute a photochemical tetrad. Irradiation of any one member results in the formation of the other three. In addition, 2,4-dimethylpyrimidine and 2,6-dimethylpyrazine also photoisomerize to 3,6-dimethylpyridazine. Irradiation of the last in the vapor state resulted in the four members of the tetrad.
POLAR EFFECTS IN THE HOMOLYTIC METHYLATION OF PYRIMIDINE: ORIENTATION AND POLYSUBSTITUTION
Giordano, Claudio,Minisci, Francesco,Tortelli, Vito,Vismara, Elena
, p. 293 - 296 (2007/10/02)
The homolytic methylation of pyrimidine in aqueous solution has been investigated with three different radical sources: tBuOOH-Fe(2+), MeCO2H-S2O8(2-)-Ag(1+), and MeSOMe-H2O2-Fe(2+).This last reagent, used for the first time in homolytic aromatic substitution, turned out to be the most efficient.The orientation of mono- and poly-methylated derivatives is discussed on the basis of polar effects.