1558-59-4

Basic information

• Product Name: 5-Aminopentanoic acid
• Synonyms: (4S)-4-Aminopentanoic acid;(S)-4-Aminovaleric acid
• CAS NO: 1558-59-4
• Molecular Formula: C₅H₁₁NO₂
• Molecular Weight: 117.15
• Mol File: 1558-59-4.mol
• Article Data: 5

Chemical Properties

• Melting Point: 212-213 °C
• Boiling Point: 241°C at 760 mmHg
• Flash Point: 99.5°C
• Appearance: /
• Density: 1.067g/cm³
• Vapor Pressure: 0.0123mmHg at 25°C
• Refractive Index: 1.463
• PKA: 4.38±0.10(Predicted)
• CAS DataBase Reference: 5-Aminopentanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Aminopentanoic acid(1558-59-4)
• EPA Substance Registry System: 5-Aminopentanoic acid(1558-59-4)

Safety Data

• Hazardous Substances Data: 1558-59-4(Hazardous Substances Data)

Usage

General Description

5-Aminopentanoic acid, also known as aminovaleric acid, is a chemical compound with the molecular formula C5H11NO2. It is an organic compound belonging to the class of alpha amino acids, which are the building blocks of proteins. 5-Aminopentanoic acid is a naturally occurring compound that can be found in the human body, as well as in some food sources such as dairy products and animal proteins. It plays a vital role in the biosynthesis of the neurotransmitter gamma-aminobutyric acid (GABA), which is involved in regulating neural excitability and promoting relaxation. 5-Aminopentanoic acid is also used in the production of certain drugs and pharmaceuticals, making it an important compound in the medical and chemical industries.

InChI:InChI=1/C5H11NO2/c1-4(6)2-3-5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/t4-/m0/s1

Upstream product

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Relevant articles and documents

Asymmetric reductive amination by a wild-type amine dehydrogenase from the thermophilic bacteria: Petrotoga mobilis

The biocatalytic reductive amination of ketone to chiral amine is one of the most challenging reactions. Using a genome-mining approach, we found proteins catalyzing the reductive amination of ketones without a carboxylic function in the α or β position. The synthesis of (4S)-4-aminopentanoic acid (ee ≥99.5%) was achieved with the thermoactive amine dehydrogenase (AmDH) AmDH4 from Petrotoga mobilis in 88% yield. The high stability and substrate tolerance make AmDH4 a very good starting point for further discovery of reductive amination biocatalysts with an enlarged substrate range. This is the first report of wild-type enzymes with related genes having proper NAD(P)H-AmDH activity.

Potent Antimicrobial Activity of Lipidated Short α,γ-Hybrid Peptides

Herein we report the potent antimicrobial activity of α,γ-hybrid lipopeptides composed of 1:1 alternating α- and γ-amino acids. Along with their potent antimicrobial activity against various Gram-positive and Gram-negative bacteria, these hybrid lipopepti

A convenient synthesis of racemic and optically active 1-aza-1,3-dienes derived from γ-amino esters: Reduction to α,β-unsaturated and saturated γ-amino acid derivatives

A simple synthesis of racemic and optically active 1-azadienes derived from γ-amino esters by olefination reaction of alkyl glyoxylates and functionalized phosphonium salts or phosphine oxides is reported. Selective reduction of these 1-azadienes with hydrides yields (E)-γ-amino-α,β-unsaturated esters. A simple procedure for the preparation of saturated γ-amino acids and γ-amino esters from the previously synthesized vinylogous amino esters is also described.