1558-97-0 Usage
General Description
Diethyl [2-(phenylthio)ethyl]malonate is an organic compound that acts as a malonate ester derivative with the chemical formula C16H20O4S. It is commonly used as a building block in organic synthesis and medicinal chemistry due to its versatile reactivity and ability to undergo various chemical transformations. diethyl [2-(phenylthio)ethyl]malonate contains a dimethyl malonate functional group and a 2-phenylthioethyl group, making it a useful intermediate for the synthesis of pharmaceuticals and agrochemicals. Additionally, it can also be utilized as a reagent in the preparation of heterocyclic compounds and as a crosslinking agent in polymer chemistry. Overall, diethyl [2-(phenylthio)ethyl]malonate is a valuable compound with various applications in the fields of chemistry and chemical engineering.
Check Digit Verification of cas no
The CAS Registry Mumber 1558-97-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,5,5 and 8 respectively; the second part has 2 digits, 9 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1558-97:
(6*1)+(5*5)+(4*5)+(3*8)+(2*9)+(1*7)=100
100 % 10 = 0
So 1558-97-0 is a valid CAS Registry Number.
InChI:InChI=1/C15H20O4S/c1-3-18-14(16)13(15(17)19-4-2)10-11-20-12-8-6-5-7-9-12/h5-9,13H,3-4,10-11H2,1-2H3
1558-97-0Relevant articles and documents
Photoredox and weak Br?nsted base dual catalysis: Alkylation of α-thio alkyl radicals
Alfonzo, Edwin,Hande, Sudhir M.
, p. 12590 - 12595 (2020)
We report the C?H activation of thioethers to α-thio alkyl radicals and their addition to electron-deficient olefins to afford alkylated products through dual photoredox and weak Br?nsted base catalysis. Mechanistic studies are consistent with a two-step activation mechanism, where oxidation of thioethers to their corresponding sulfide radical cations by an acridinium photoredox catalyst is followed with deprotonation by trifluoroacetate to generate α-thio alkyl radicals and trifluoroacetic acid (TFA). Experimental studies support the involvement of TFA in all subsequent steps leading to product formation.
