1559-88-2 Usage
Description
1-Bromo-2,3,5,6-tetrafluorobenzene is a clear colorless liquid that serves as a crucial intermediate in the synthesis of various organic compounds and has significant applications in the pharmaceutical industry.
Uses
Used in Chemical Synthesis:
1-Bromo-2,3,5,6-tetrafluorobenzene is used as a key intermediate for the production of 1,2,4,5-tetrafluoro-3-hept-1-ynyl-benzene, a compound with potential applications in various chemical processes.
Used in Pharmaceutical Industry:
1-Bromo-2,3,5,6-tetrafluorobenzene is used as a pharmaceutical intermediate for the synthesis of various drugs and medicinal compounds. Its unique chemical structure allows for the development of new pharmaceuticals with improved properties and therapeutic effects.
Used in Fluorine Chemistry:
Due to its tetrafluorinated structure, 1-Bromo-2,3,5,6-tetrafluorobenzene can be utilized in fluorine chemistry for the preparation of fluorinated derivatives with potential applications in various industries, including pharmaceuticals, agrochemicals, and materials science.
Check Digit Verification of cas no
The CAS Registry Mumber 1559-88-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,5,5 and 9 respectively; the second part has 2 digits, 8 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1559-88:
(6*1)+(5*5)+(4*5)+(3*9)+(2*8)+(1*8)=102
102 % 10 = 2
So 1559-88-2 is a valid CAS Registry Number.
InChI:InChI=1/C6H3ClFI/c7-5-3-4(9)1-2-6(5)8/h1-3H
1559-88-2Relevant articles and documents
Bolton,Sandall
, p. 540 (1976)
Copper-catalyzed hydrodefluorination of fluoroarenes by copper hydride intermediates
Lv, Hongbin,Cai, Yuan-Bo,Zhang, Jun-Long
supporting information, p. 3203 - 3207 (2013/04/23)
Breaking bad: Efficient copper-catalyzed C-F bond activation has been achieved by replacing fluorine with hydrogen. A copper hydride is proposed as the active intermediate, which proceeds through a nucleophilic attack on the fluorocarbon, as determined by experimental and theoretical results (see structure; C gray, H white, Cu light red, F light blue; distances in ?).
Reactions of dibromotetrafluorobenzene derivatives with sodium phenoxide salts. Competing hydrodebromination and SNAr processes
Banks, Benjamin,Cargill, Matthew R.,Sandford, Graham,Tadeusiak, Andrzej J.,Westemeier, Hauke,Yufit, Dmitrii S.,Howard, Judith A.K.,Kilickiran, Pinar,Nelles, Gabrielle
scheme or table, p. 627 - 634 (2010/07/03)
1,2- and 1,3-dibromotetrafluorobenzene react with sodium phenoxide derivatives at sites para to ring bromine because these positions are activated by fluorine atoms ortho and meta to the site of nucleophilic substitution. Fluorine para to the site of nucl
