15598-88-6

Basic information

• Product Name: 3-propyl-1-adamantanol
• Synonyms: 3-propyl-1-adamantanol
• CAS NO: 15598-88-6
• Molecular Formula: C13H22O
• Molecular Weight: 194.31318
• Mol File: 15598-88-6.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-propyl-1-adamantanol(CAS DataBase Reference)
• NIST Chemistry Reference: 3-propyl-1-adamantanol(15598-88-6)
• EPA Substance Registry System: 3-propyl-1-adamantanol(15598-88-6)

Safety Data

• Hazardous Substances Data: 15598-88-6(Hazardous Substances Data)

Upstream product

• 20778-55-6 1-n-propyl-adamantane 
• 80121-64-8 1-bromo-3-n-propyladamantane 
• 20778-55-6 1-n-propyladamantane 

Relevant articles and documents

Synthesis and biological evaluation of memantine nitrates as a potential treatment for neurodegenerative diseases

A series of memantine nitrate derivatives, as dual functional compounds with neuroprotective and vasodilatory activity for neurodegenerative diseases, was designed and synthesized. These compounds combined the memantine skeleton and a nitrate moiety, and thus inhibited the N-methyl-d-aspartic acid receptor and released NO in the central nervous system. The biological evaluation results revealed that the new memantine nitrates were effective in protecting neurons against glutamate-induced injury in vitro. Moreover, memantine nitrates dilated aortic rings against phenylephrine-induced contraction. The structure-activity relationships of neuroprotection and vasodilation were both analyzed. In further studies, compound MN-05 significantly protected cortical neurons by inhibiting Ca2+ influx, reducing free radical production and maintaining the mitochondrial membrane potential. Further research on MN-05 is warranted.