1560-11-8 Usage
Description
1-Cyclopentenecarboxylic acid is a white to pale yellow powder with chemical properties that make it suitable for various applications in the fields of pharmaceuticals and organic chemistry. It is an organic compound that has been evaluated for its potential as an effective anticonvulsant during the Anticonvulsant Screening Program (ASP) of the Antiepileptic Drug Development Program.
Uses
1. Used in Pharmaceutical Applications:
1-Cyclopentenecarboxylic acid is used as a key intermediate in the synthesis of various pharmaceutical compounds. Its application in this industry is due to its ability to participate in enantioselective 1,3-dipolar cycloadditions of diazoacetates and solid-phase synthesis of substituted indolines.
2. Used in Organic Chemistry:
1-Cyclopentenecarboxylic acid is used as a reactant in the synthesis of various organic compounds, such as cis-8-hexahydroindanecarboxylic acid via Diels-Alder reaction with butadiene and in the synthesis of isoxazole derivatives. Its application in this field is attributed to its reactivity and versatility in chemical reactions.
3. Used in Antagonist Development:
1-Cyclopentenecarboxylic acid is used as a starting material for the development of antagonists for A1and A2-adenosine receptors. Its application in this area is due to its potential to modulate these receptors, which can have therapeutic implications in various conditions.
4. Used in Anticonvulsant Research:
1-Cyclopentenecarboxylic acid has been evaluated as a new effective anticonvulsant during the Anticonvulsant Screening Program (ASP) of the Antiepileptic Drug Development Program. Its application in this field is based on its potential to provide relief from seizures and improve the quality of life for patients with epilepsy.
Check Digit Verification of cas no
The CAS Registry Mumber 1560-11-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,5,6 and 0 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1560-11:
(6*1)+(5*5)+(4*6)+(3*0)+(2*1)+(1*1)=58
58 % 10 = 8
So 1560-11-8 is a valid CAS Registry Number.
InChI:InChI=1/C6H8O2/c7-6(8)5-3-1-2-4-5/h3H,1-2,4H2,(H,7,8)/p-1
1560-11-8Relevant articles and documents
Alt,G.H.,Speziale,A.J.
, p. 1340 - 1342 (1966)
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Wheeler,Lerner
, p. 63 (1956)
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Macrolactam Synthesis via Ring-Closing Alkene-Alkene Cross-Coupling Reactions
Goh, Jeffrey,Loh, Teck-Peng,Maraswami, Manikantha
supporting information, p. 9724 - 9728 (2020/12/21)
Reported herein is a practical method for macrolactam synthesis via a Rh(III)-catalyzed ring closing alkene-alkene cross-coupling reaction. The reaction proceeded via a Rh-catalyzed alkenyl sp2 C-H activation process, which allows access to macrocyclic molecules of different ring sizes. Macrolactams containing a conjugated diene framework could be easily prepared in high chemoselectivities and Z,E stereoselectivities.
Macrolide Synthesis through Intramolecular Oxidative Cross-Coupling of Alkenes
Jiang, Bing,Zhao, Meng,Li, Shu-Sen,Xu, Yun-He,Loh, Teck-Peng
supporting information, p. 555 - 559 (2018/02/21)
A RhIII-catalyzed intramolecular oxidative cross-coupling between double bonds for the synthesis of macrolides is described. Under the optimized reaction conditions, macrocycles containing a diene moiety can be formed in reasonable yields and with excellent chemo- and stereoselectivity. This method provides an efficient approach to synthesize macrocyclic compounds containing a 1,3-conjugated diene structure.
