1562-34-1 Usage
Description
Phenyl vinylsulfonate, an ester, is a chemical compound derived from the reaction of phenyl vinylsulfonate with various alkyl furan derivatives, yielding the corresponding cycloadducts. It has been reported that a palladium complex, derived from a tetraphosphine-catalyzed Heck vinylation of phenyl vinylsulfonate, has been synthesized.
Uses
1. Used in Chemical Synthesis:
Phenyl vinylsulfonate is used as a reactant for the synthesis of various chemical compounds, particularly in the formation of cycloadducts with alkyl furan derivatives. This application is due to its reactivity and ability to form stable products with a wide range of substrates.
2. Used in Catalyst Development:
Phenyl vinylsulfonate is used as a precursor in the development of palladium complexes, which are essential catalysts in various chemical reactions. The application reason is its ability to undergo a tetraphosphine-catalyzed Heck vinylation, leading to the formation of a palladium complex with potential catalytic properties.
3. Used in Pharmaceutical Research:
Phenyl vinylsulfonate may be used as a starting material or intermediate in the development of new pharmaceutical compounds. The application reason is its unique chemical structure, which can be further modified or functionalized to create novel drug candidates with potential therapeutic applications.
4. Used in Material Science:
Phenyl vinylsulfonate can be utilized in the development of new materials with specific properties, such as polymers with tailored characteristics. The application reason is its ability to undergo various chemical reactions, allowing for the creation of a diverse range of materials with different properties and potential applications.
5. Used in Environmental Applications:
Phenyl vinylsulfonate may be employed in the development of environmentally friendly processes or products, such as green chemistry applications. The application reason is its potential to be used as a building block for more sustainable chemical processes, reducing the environmental impact of certain industrial activities.
Check Digit Verification of cas no
The CAS Registry Mumber 1562-34-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,5,6 and 2 respectively; the second part has 2 digits, 3 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1562-34:
(6*1)+(5*5)+(4*6)+(3*2)+(2*3)+(1*4)=71
71 % 10 = 1
So 1562-34-1 is a valid CAS Registry Number.
InChI:InChI=1/C8H8O3S/c1-2-12(9,10)11-8-6-4-3-5-7-8/h2-7H,1H2
1562-34-1Relevant articles and documents
MILD AND PRACTICAL CYCLOADDITION REACTIONS OF FURANS WITH PHENYL VINYL SULFONATE
Klein, Larry L.,Deeb, Thomas M.
, p. 3935 - 3938 (1985)
Phenyl vinyl sulfonate reacts with various alkyl furan derivatives under mild conditions to produce excellent yields of the corresponding cycloadducts.
Novel Hybrid Conjugates with Dual Suppression of Estrogenic and Inflammatory Activities Display Significantly Improved Potency against Breast Cancer
Ning, Wentao,Hu, Zhiye,Tang, Chu,Yang, Lu,Zhang, Silong,Dong, Chune,Huang, Jian,Zhou, Hai-Bing
supporting information, p. 8155 - 8173 (2018/08/09)
In this work, we developed a small library of novel OBHS-RES hybrid compounds with dual inhibition activities targeting both the estrogen receptor α (ERα) and NF-?B by incorporating resveratrol (RES), a known inhibitor of NF-?B, into a privileged indirect antagonism structural motif (OBHS, oxabicycloheptene sulfonate) of estrogen receptor (ER). The OBHS-RES conjugates could bind well to ER and showed remarkable ERα antagonistic activity, and they also exhibited excellent NO inhibition in macrophage RAW 264.7 cells. Compared with 4-hydroxytamoxifen, some of them showed better antiproliferative efficacy in MCF-7 cell lines with IC50 up to 3.7 μM. In vivo experiments in a MCF-7 breast cancer model in Balb/c nude mice indicated that compound 26a was more potent than tamoxifen. Exploration of the compliancy of the structure against ER specificity utilizing these types of isomeric three-dimensional ligands indicated that one enantiomer had much better biological activity than the other.
Novel Bioactive Hybrid Compound Dual Targeting Estrogen Receptor and Histone Deacetylase for the Treatment of Breast Cancer
Tang, Chu,Li, Changhao,Zhang, Silong,Hu, Zhiye,Wu, Jun,Dong, Chune,Huang, Jian,Zhou, Hai-Bing
supporting information, p. 4550 - 4572 (2015/06/25)
A strategy to develop chemotherapeutic agents by combining several active groups into a single molecule as a conjugate that can modulate multiple cellular pathways may produce compounds having higher efficacy compared to that of single-target drugs. In th