156281-04-8Relevant articles and documents
5-Alkyltryptamine derivatives as highly selective and potent 5-HT(1D) receptor agonists
Slassi, Abdelmalik,Edwards, Louise,O'Brien, Anne,Meng, Charles Q.,Xin, Tao,Seto, Caroline,Lee, David K.H.,MacLean, Neil,Hynd, Donna,Chen, Cora,Wang, Hong,Kamboj, Rajender,Rakhit, Suman
, p. 1707 - 1709 (2007/10/03)
A series of 5-alkyltryptamines (6) and the corresponding conformationally constrained analogues (8) have been synthesized. The structure-activity relationships (SAR) at the 5-position of the indole skeleton and the ethylamine side chain have been studied.