156281-11-7Relevant articles and documents
Methanesulfinylation of Benzyl Halides with Dimethyl Sulfoxide
Fu, Duo,Dong, Jun,Du, Hongguang,Xu, Jiaxi
, p. 2752 - 2758 (2020/01/31)
A phenyltrimethylammonium tribromide-mediated nucleophilic substitution/oxygen transformation reaction of benzyl halides with DMSO has been developed. In this transition-metal-free reaction, DMSO acts as not only a solvent but also a "S(O)Me" source, thus providing a convenient method for the efficient and direct synthesis of various benzyl methyl sulfoxides.
General solvent-free highly selective N-tert-butyloxycarbonylation strategy using protic ionic liquid as an efficient catalyst
Majumdar, Swapan,De, Jhinuk,Chakraborty, Ankita,Maiti, Dilip K.
, p. 24544 - 24550 (2014/07/07)
A simple, rapid and solvent-free protocol is described for the chemo-selective transformation of amines to tert-butyloxycarbonyl protected derivatives (NHBoc) using Boc2O and imidazolium trifluoroacetate protic ionic liquid (5-20 mol%). Unwanted side products such as isocyanate, urea or N,N-di-Boc were not detected. The scope of the protection strategy was successfully explored for substrate alcohols, phenols and thiol at elevated temperatures. Optically pure amino acids, amino acid esters and amino alcohols were efficiently converted to the corresponding N-Boc protected derivatives in excellent yields without racemization at the chiral center. The distinct advantages of this method are: operational simplicity, cleaner reaction, high selectivity, excellent yield, rapid reaction convergence, easy preparation and recyclability of the catalyst.
On catalysis by ionic liquids
Chakraborti, Asit K.,Roy, Sudipta Raha
supporting information; experimental part, p. 6902 - 6903 (2009/09/26)
-
